Tumors of the Central Nervous System, Volume 8 (eBook)

Astrocytoma, Medulloblastoma, Retinoblastoma, Chordoma, Craniopharyngioma, Oligodendroglioma, and Ependymoma

M.A. Hayat (Herausgeber)

eBook Download: PDF

2012 | 2012
XXXVII, 347 Seiten
Springer Netherland (Verlag)
978-94-007-4213-0 (ISBN)

Infos

With tens of thousands of new CNS tumor cases each year in the US alone, this series of publications is a valuable aid to the diagnosis and treatment of these problematic neoplasms. Now, the eighth in the set returns to the topic of brain tumors, dealing with seven distinct types: astrocytoma, medulloblastoma, retinoblastoma, chordoma, craniopharyngioma, oligodendroglioma, and ependymoma. After updating the classification of medulloblastoma the volume provides an overview of ependymoma as well as describing the delineation of prognosis based on the genetic aberrations of the latter patients. The material offers key insights into the molecular pathways involved in tumor biology, such as the role of E-cadherin gene instability, carbonic anhydrase II, urokinase plasminogen activator, and Wnt signaling in meningioma. Contributors explain the genetic and clinical features associated with recurring meningioma, including the role played by erythropoietin receptor, and examine the way in which OTX2 transcription factor functions as an oncogene in medulloblastoma. With much more besides, including discussion of the molecular mechanisms that result in resistance to chemotherapy in medulloblastoma, this volume and its companions have a positive role to play in inspiring a new generation of researchers to design new drugs that are better targeted-and thus more effective.

Inhalt

Table of Contents: TCNS Volume 8AstrocytomaChapter 1. astrocytoma cell line: role of brain natriuretic peptidechapter 2. malignant brain astrocytomas: extent of resection affects survivalmedulloblastoma chapter 3. medulloblastoma: classification (a review)chapter 4. medulloblastomas: clinically important microrna geneschapter 5. medulloblastoma: role of otx2 transcription factorschapter 6. molecular mechanisms of chemoresistance in medulloblastomachapter 7. extraneural metastasis in medulloblastomaChapter 8. Medulloblastoma: Therapy with Bortezomib/Tumor Necrosis factor-related apoptosis-inducing ligand chapter 9.standard-risk medulloblastoma: hyperfractionated radiotherapyretinoblastoma chapter 10. retinoma and retinoblastoma: genomic hybridisationchapter 11. cell cycle control by ataxia telangiectasia mutated protein through regulating retinoblastoma protein phosphorylationchapter 12. role of survivin in retinoblastoma: diagnosis and prognosischapter 13. retinoblastoma: the role of epigeneticschapter 14. retinoblastoma: disease, diagnosis, therapy and managementchapter 15. long-term survivors of retinoblastoma: risk of increased second malignancychapter 16. new cancers among long-term survivors of retinoblastomachordoma chapter 17. chordoma: role of cam5.2chapter 18. chordomas and chondrosarcomas: treatment with particle radiotherapychapter 19. skull base chordomas: endonasal endoscopic transclival approachcraniopharyngiomachapter 20. craniopharyngioma: comparison between supra-orbital versus endonasal keyhole approacheschapter 21. the expanded endoscopic endonasal approach for primary and recurrent craniopharyngiomaschapter 22. craniopharyngioma: the role of radiationchapter 23. cystic craniopharyngiomas: intratumoral bleomycin therapyoligodendroglioma chapter 24. anaplastic oligodendroglioma metastasized to extraneural siteschapter 25. recurrent oligodendroglioma: treatment with bevacizumabependymoma chapter 26. ependymoma: an overviewchapter 27. ependymomas: prognosis based on genetic aberrationschapter 28. aberrant dna methylation in ependymomaschapter 29. progressively metastasizing ependymoma: genomic aberrationschapter 30. extradural ependymoma: diagnosis using magnetic resonance imagingchapter 31. primary malignant ependymoma of the abdominal cavity: diagnosischapter 32. atypical histologic features and patterns of malignant evolution in tanycytic ependymomachapter 33. intracranial ependymoma: role for chemotherapy.

Produkt-Details

• Erscheint lt. Verlag: 14.6.2012
• Reihe/Serie: Tumors of the Central Nervous System
• Reihe/Serie: Tumors of the Central Nervous System
• Zusatzinfo: XXXVII, 338 p. 50 illus., 38 illus. in color.
• Verlagsort: Dordrecht
• Sprache: englisch
• Themenwelt: Medizin / Pharmazie ► Allgemeines / Lexika
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Allgemeinmedizin
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Neurologie
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie
• Themenwelt: Medizin / Pharmazie ► Studium
• Themenwelt: Naturwissenschaften ► Biologie ► Humanbiologie
• Themenwelt: Naturwissenschaften ► Biologie ► Zoologie
• Schlagworte: Assessment of cancer treatments • cancer diagnosis • Cancer drug development • Cancer prognosis • Cancer Therapy
• ISBN-10: 94-007-4213-4 / 9400742134
• ISBN-13: 978-94-007-4213-0 / 9789400742130