Arenaviruses

Genes, Proteins, and Expression

Buch | Softcover

VII, 116 Seiten

2011 | 1. Softcover reprint of the original 1st ed. 1987
Springer Berlin (Verlag)
978-3-642-71685-0 (ISBN)

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M. B. A. OLDSTONE Viruses are generally studied either because they cause significant human, animal or plant disease or for their utility as materials to probe a basic phenomenon in biology, chemistry, genetics or molecular biology. Arenaviruses are unusually interesting in that they occupy both of these categories. Arenaviruses cause severe human diseases known primarily as the hemor rhagic fevers occurring in South and Latin America (Bolivia: Machupo virus and Argentina: Junin virus) and in Africa (Lassa virus). Because such viruses produce profound disability and may kill the persons they infect, they are a source of economic hardship in the countries where they are prevalent. Further, they provide new problems for health care personnel owing to the narrowing of the world as visitors from many countries increasingly travel to and from these endemic areas. In addition, lymphocytic choriomeningitis virus (LCMV) can infect humans worldwide, although the illness is most often less disabling than those elicited by other arenaviruses. Yet LCMV is likely of greater concern to non-arena-virologists and experimentalists using tissue culture or animals, i. e. , workers in molecular biology, cancer research, virology, immunobiology, etc. , because normal appearing cultured cells or tissues and animals used for research may be persistently infected with LCMV without manifesting clinical disease or cytopathology and transmit that infection to laboratory workers (reviewed OWSTONE and PETERS 1978). For example, HINMAN et al.

The Arenaviruses - An Introduction.- Arenavirus Gene Structure and Organization. With 6 Figures.- Sequence Comparison Among Arenaviruses. With 1 Figure.- Protein Structure and Expression Among Arenaviruses. With 7 Figures.- Mapping Arenavirus Genes Causing Virulence.- State of Viral Genome and Proteins During Persistent Lymphocytic Choriomeningitis Virus Infection. With 11 Figures.- Pathology and Pathogenesis of Arenavirus Infections. With 14 Figures.

Erscheint lt. Verlag	17.11.2011
Reihe/Serie	Current Topics in Microbiology and Immunology
Zusatzinfo	VII, 116 p.
Verlagsort	Berlin
Sprache	englisch
Maße	170 x 244 mm
Gewicht	235 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Dermatologie
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Mikrobiologie / Infektologie / Reisemedizin
	Studium ► Querschnittsbereiche ► Infektiologie / Immunologie
	Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie
Schlagworte	Diseases • Genetics • Immunobiology • Infection • Molecular Biology • Pathology • Protein • proteins • Virology • Virus
ISBN-10	3-642-71685-7 / 3642716857
ISBN-13	978-3-642-71685-0 / 9783642716850
Zustand	Neuware