Modern Clinical Molecular Techniques (eBook)

Madhuri Hegde, Peter Hu, Patrick Alan Lennon (Herausgeber)

eBook Download: PDF

2012 | 2012
XIII, 436 Seiten
Springer New York (Verlag)
978-1-4614-2170-2 (ISBN)

Infos

This timely book covers the need to know clinical practices for all those involved in molecular laboratory science. The field of molecular medicine is evolving at an astounding speed. Propelled by the new insights and technologies, advances are being made at an unprecedented rate. With dual measure given to today's breakthroughs, this book is a collection of the most current practices relevant to the clinical molecular laboratorian. It begins with an introductory section on techniques and procedure.  It then presents four separate sections on infectious disease, oncology, pre/post-natal, and identity testing, with specific chapters clearly outlining clinical protocols used in daily practice.

Modern Clinical Molecular Techniques cuts to the heart of what is essential for the practicing molecular laboratory scientist. It is an outstanding resource for those operating within or looking to set up a clinical molecular laboratory.

Inhalt

PrefaceAcknowledgementContributors  Section I   Current Molecular Laboratory Methods 1        Specimen Collection, Handling and ProcessingLindsy Hengesbach and John Gerlach 2        DNA/RNA Isolation and QuantitationJing Wang 3        Test ValidationCindy McCloskey and S Terence Dunn 4        In Vitro Amplification Methods in Molecular DiagnosticsC. Alexander Valencia and Bradford Coffee 5        Whole Genome Sequencing in the Clinical LaboratoryTina Hambuch, Brad Sickler, Arnold Liao, Suneer Jain, and Philip D. Cotter 6        Estimation of Exon Dosage Using Real-Time Quantitative Polymerase Chain ReactionJuliana Purrazzella and Arupa Ganguly 7        Reporting Clinical Molecular Genetic Laboratory ResultsVictor Wei Zhang and Lora J. H. Bean  Section II Clinical Molecular Infectious Disease Testing 8        HIV-1 Genotyping and Virtual PhenotypingFangling Xu and Jianli Dong 9        COBAS® Ampliprep/Taqman HIV-1 TestTavat A. Buraruk and Charles E. Stager 10    Hepatitis C Virus (HCV) Genotype Assay (LiPA)Charles E. Stager and Tavat A. Buraruk 11    COBAS® Ampliprep/Taqman HCV TestCharles E. Stager and Tavat A. Buraruk 12    Epstein-Barr Virus and Cytomegalovirus Viral Load Monitoring by Quantitative Real-Time Polymerase Chain ReactionSu S. Chen, Seema Hai, and Rajyalakshmi Luthra 13    Quantification of BK Viral LoadHai Wu and Jianli Dong 14    Molecular Diagnosis and Epidemiology of RabiesRodney E. Rohde and Bonny C. Mayes 15    Pyrosequencing for Bacterial IdentificationLaura Millecker and Ruth Ann Luna 16    Other Pathogens of Significant Public Health ConcernChris L. McGowin, Rodney E. Rohde, and Greg C. Whitlock   Section III Clinical Molecular Oncology Testing 17    Gene Rearrangements TestingSiby Sebastian, Juan Du, and Rizwan Naeem 18    Mutation Analysis in CancerKeyur Pravinchandra Patel, John Galbincea,  and Rajyalakshmi Luthra 19    Minimal Residual DiseaseWesley Greaves and Rajyalakshmi Luthra 20    Pyrosequencing in CancerBedia A. Barkoh, Rajyalakshmi Luthra, and Shalini Verma 21    Clinical Applications of Microarrays in CancerMarilyn M. Li, Ankita Patel, and Xiaofeng Hu 22    Basic Theories and Clinical Applications of Molecular Flow CytometryHua Kang Wu, Hongli Chen, and Peter Hu  Section IV Clinical Molecular Pre/Postnatal Testing 23    Molecular Prenatal Diagnostic TestingJoanna Wiszniewska and Christine M. Eng 24    PCR Based Diagnosis of Fragile X Syndrome  Daniel J. Dykas and Allen E. Bale  Section V Human Identity Testing 25    Microsatellite Testing Short Tandem Repeat Profile GenerationRobin DeVille Guidry and Laura Gahn 26    ParentageLaura Gahn and Robin DeVille Guidry  Section VI Clinical Molecular Training 27    Diagnostic Molecular Training Peter Hu, Patrick A. Lennon, and Madhuri Hegde 28    Molecular Diagnostics Point of Care Testing TrainingChang W. Lee, and Peter Hu 

Produkt-Details

• Erscheint lt. Verlag: 11.5.2012
• Zusatzinfo: XIII, 436 p. 60 illus., 41 illus. in color.
• Verlagsort: New York
• Sprache: englisch
• Themenwelt: Sachbuch/Ratgeber ► Gesundheit / Leben / Psychologie ► Krankheiten / Heilverfahren
• Themenwelt: Medizin / Pharmazie ► Allgemeines / Lexika
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie
• Themenwelt: Studium ► 2. Studienabschnitt (Klinik) ► Pathologie
• Themenwelt: Naturwissenschaften ► Biologie
• Themenwelt: Technik
• Schlagworte: amplification • DNA • Electrophoresis • Genetics • Genotype • Infectious Diseases
• ISBN-10: 1-4614-2170-5 / 1461421705
• ISBN-13: 978-1-4614-2170-2 / 9781461421702