Comparative Gene Finding

Models, Algorithms and Implementation

Marina Axelson-Fisk (Autor)

Buch | Softcover

304 Seiten

2012 | Previously published in hardcover
Springer London Ltd (Verlag)
978-1-4471-2539-6 (ISBN)

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Comparative genomics is a new and emerging ?eld, and with the explosion of ava- able biological sequences the requests for faster, more ef?cient and more robust algorithms to analyze all this data are immense. This book is meant to serve as a self-contained instruction of the state-of-the-art of computational gene ?nding in general and of comparative approaches in particular. It is meant as an overview of the various methods that have been applied in the ?eld, and a quick introduction into how computational gene ?nders are built in general. A beginner to the ?eld could use this book as a guide through to the main points to think about when constructing a gene ?nder, and the main algorithms that are in use. On the other hand, the more experienced gene ?nder should be able to use this book as a reference to different methods and to the main components incorporated in these methods. I have focused on the main uses of the covered methods and avoided much of the technical details and general extensions of the models. In exchange I have tried to supply references to more detailed accounts of the different research areas touched upon. The book, however, makes no claim on being comprehensive.

Single Species Gene Finding.- Sequence Alignment.- Comparative Gene Finding.- Gene Structure Submodels.- Parameter Training.- Implementation of a Comparative Gene Finder.

Erscheint lt. Verlag	5.5.2012
Reihe/Serie	Computational Biology ; 11
Zusatzinfo	XV, 304 p.
Verlagsort	England
Sprache	englisch
Maße	155 x 235 mm
Themenwelt	Informatik ► Weitere Themen ► Bioinformatik
	Naturwissenschaften ► Biologie ► Biochemie
	Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie
Schlagworte	Bioinformatics • Biological sequence analysis • comparative genomics • Computational Biology • Computational Gene Finding • sequence alignment
ISBN-10	1-4471-2539-8 / 1447125398
ISBN-13	978-1-4471-2539-6 / 9781447125396
Zustand	Neuware