Emerging Health Trends
Addison Wesley
978-0-13-303957-3 (ISBN)
Right now, science is transforming what we know about preserving and improving human health. These three extraordinary books take you to the cutting edge of emerging science, presenting new findings that might someday save your life. In Antibiotic Resistance: Understanding and Responding to an Emerging Crisis, Karl S. Drlica and David S. Perlin presents a thorough and authoritative overview of the growing resistance of pathogenic bacteria to antibiotics, and what this means to our ability to control and treat infectious diseases. The authors answer crucial questions such as: What is resistance? How does it emerge? How do common human activities promote resistance? What can we do about it? How can we strengthen our defenses against resistance, minimize our risks, extend the effectiveness of current antibiotics, and find new ones faster? Next, in Chips, Clones, and Living Beyond 100: How Far Will the Biosciences Take Us?, Paul and Joyce A. Schoemaker tour the remarkable field of biosciences as it stands today, and preview the directions and innovations that are most likely to emerge in the coming years. They offer a clear, non-technical overview of crucial current developments that are likely to have enormous impact, addressing issues ranging from increased human longevity to global warming, bio-warfare to personalized medicine. Along the way, they illuminate each of the exciting technologies and hot-button issues associated with contemporary biotechnology - including stem cells, cloning, probiotics, DNA microarrays, proteomics, gene therapy, and more. Finally, in It Takes a Genome, Greg Gibson posits a revolutionary new hypothesis: our genome is out of equilibrium, both with itself and its environment. Our bodies weren’t designed to subsist on fat and sugary foods; our immune systems aren’t designed for today’s clean, bland environments; our minds aren’t designed to process hard-edged, artificial electronic inputs from dawn ‘til midnight. That, says Gibson, is why so many of us suffer from chronic diseases that barely touched our ancestors. Gibson reveals the stunningly complex ways genes cooperate and interact; illuminates the genetic “mismatches” that lead to cancer, diabetes, inflammatory and infectious diseases, AIDS, depression, and senility; and considers surprising new evidence for genetic variations in human psychology.
From world-renowned leaders and experts, including Karl S. Drlica, David S. Perlin, Paul J. H. Schoemaker, Joyce A. Schoemaker, and Greg Gibson
Karl Drlica, Ph.D. is Principal Investigator at the Public Health Research Institute Center of the UMDNJ-New Jersey Medical School. His laboratory focuses on fluoroquinolone action and resistance with M. tuberculosis and other bacteria, including approaches to slowing the enrichment and amplification of resistant bacterial subpopulations. Dr. David S. Perlin is a Principal Investigator at the Public Health Research Institute (PHRI) of the UMDNJ-New Jersey Medical School. His laboratory explores mechanisms of antifungal drug resistance, rapid detection of bloodstream pathogens in high-risk patients, discovery of novel molecules to combat tuberculosis, and the development of small animal models for respiratory pathogens. Paul Schoemaker is Research Director of the Mack Center for Technological Innovation at the Wharton School. He is founder and chairman of Decision Strategies International, Inc., a consulting and training firm specializing in strategic planning and executive development. He has written over 70 academic and applied papers, and co-author or editor of several books including Wharton On Managing Emerging Technologies, Winning Decisions, and Profiting from Uncertainty. Joyce A. Schoemaker is a biotech consultant and biology course instructor. Greg Gibson is Professor of Genetics at North Carolina State University in Raleigh, and of Integrative Biology at the University of Queensland, Australia. A leader in the new field of genomics, he serves on the editorial boards of PLoS Genetics, Current Biology, and Genetics. With Spencer V. Muse, he co-authored A Primer of Genome Science, one of the field’s leading textbooks.
Antibiotic Resistance: Understanding and Responding to an Emerging Crisis
Preface xv
Chapter 1 Introduction to the Resistance Problem 1
Chapter 2 Working with Pathogens 17
Chapter 3 A Survey of Antibiotics 31
Chapter 4 Dosing to Cure 55
Chapter 5 Emergence of Resistance 73
Chapter 6 Movement of Resistance Genes Among Pathogens 91
Chapter 7 Transmission of Resistant Disease 105
Chapter 8 Surveillance 125
Chapter 9 Making New Antibiotics 139
Chapter 10 Restricting Antibiotic Use and Optimizing Dosing 149
Chapter 11 Influenza and Antibiotic Resistance 167
Chapter 12 Avoiding Resistant Pathogens 177
Afterword A Course of Action 203
Appendix A Molecules of Life 207
Appendix B Microbial Life Forms 221
Glossary 227
Literature Cited 233
Index 251
Chips, Clones, and Living Beyond 100: How Far Will the Biosciences Take Us?
Foreword xii
Preface xiv
Chapter 1 Living well beyond 100 1
Chapter 2 A short history of biomedicine 21
Chapter 3 Snapshot of the biosciences 35
Chapter 4 Bio-driven convergence 57
Chapter 5 The business of biomedicine 79
Chapter 6 Healthcare under stress 101
Chapter 7 Wildcards for the future 125
Chapter 8 Scenarios up to 2025 143
Chapter 9 What it all means 163
Appendix A DNA, RNA, and protein 177
Appendix B Cloning genes 183
Appendix C Complexity of the genome 187
Glossary of Biomedical Terms 191
Acknowledgments 199
About the Authors 201
Index 203
It Takes a Genome: How a Clash Between Our Genes and Modern Life Is Making Us Sick
Preface: How a genetic culture clash with modern life is making us sick ix
Chapter 1: The adolescent genome 1
Chapter 2: Breast cancer’s broken genes 19
Chapter 3: Not so thrifty diabetes genes 41
Chapter 4: Unhealthy hygiene 65
Chapter 5: Genetic AIDS 85
Chapter 6: Generating depression 99
Chapter 7: The alzheimer’s generation 121
Chapter 8: Genetic normality 135
Endnotes 151
About the author 175
Index 177
| Erscheint lt. Verlag | 20.2.2012 |
|---|---|
| Verlagsort | Boston |
| Sprache | englisch |
| Gewicht | 1 g |
| Themenwelt | Sachbuch/Ratgeber ► Gesundheit / Leben / Psychologie |
| Naturwissenschaften ► Biologie | |
| ISBN-10 | 0-13-303957-9 / 0133039579 |
| ISBN-13 | 978-0-13-303957-3 / 9780133039573 |
| Zustand | Neuware |
| Haben Sie eine Frage zum Produkt? |
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