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Infection, Immune Homeostasis and Immune Privilege

Joan Stein-Streilein (Herausgeber)

Buch | Hardcover
XII, 156 Seiten
2012 | 2012
Springer Basel (Verlag)
978-3-0348-0444-8 (ISBN)

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This book highlights mechanisms leading to immune privilege in tissues and organs, the deviation of immune responses and the modification of the behavior of the immune cells that manage to cross the blood barriers of tissues, in the context of infection.

Organs and tissues that can tolerate little or no inflammation have developed multiple overlapping mechanisms of immune protection in the absence of inflammation. These areas have been designated "immune-privileged sites" by Peter Medawar and include the central nervous system, eye, reproductive tract, testis and possibly the liver. Mechanisms of immune homeostasis found in less immune-regulated organs are often evident in the immune privileged sites and vice versa. It is important that the non-inflammatory mechanisms that contribute to immune privilege allow host defense against infectious organisms.

This volume highlights the mechanisms leading to immune privilege in tissues and organs, the deviation of immune responses and the modification of the behavior of the immune cells that manage to cross the blood barriers of tissues, in the context of infection.

Introduction.- The Eye as Immune Privileged Site.- Immune Privilege of the Testis - Meaning, Mechanisms and Manifestations.- The Role of Intrauterine Immune Privilege in Perinatal Infectious Diseases.- The Liver as an Immune Privileged Site.- Immune Homeostasis of the Lung: The Role of Regulatory NKT Cells in Asthma.- Immune Homeostasis of the Gut.

Erscheint lt. Verlag 4.7.2012
Reihe/Serie Birkhäuser Advances in Infectious Diseases
Zusatzinfo XII, 156 p.
Verlagsort Basel
Sprache englisch
Maße 155 x 235 mm
Gewicht 378 g
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Mikrobiologie / Infektologie / Reisemedizin
Medizin / Pharmazie Studium
Naturwissenschaften Biologie Genetik / Molekularbiologie
Schlagworte immune homeostasis • immune privilege • inflammation
ISBN-10 3-0348-0444-X / 303480444X
ISBN-13 978-3-0348-0444-8 / 9783034804448
Zustand Neuware
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