Role of HPIP, a cytoplasmic regulator of ER-Alpha in microtubule dynamics

Rajasekar Gunasekaran (Autor)

Buch | Softcover

60 Seiten

2011 | 2. Auflage
GRIN Verlag
978-3-656-07884-5 (ISBN)

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Master's Thesis from the year 2009 in the subject Chemistry - Bio-chemistry, grade: 9.12, , course: Medical Biotechnology - Protein Biochemistry, language: English, abstract: Cancer being a complex disease is well implicated to deregulated activity of numerous cellular proteins ultimately accounting for functions of cell division and survival etc.Molecular oncological evidences point microtubules and their associated proteins called MAPs as one of the most vital proteins to elicit tumour malignancy at the cellular level.In this dissertation, a MAP protein called HPIP has been investigated for its role in polymerization of cytoskeleton, microtubules and cancer disease progression.Preliminary lines of experiment conducted under in vitro conditions enabled us to interpret HPIP as a factor promoting the polymerization of microtubules, the head apparatus for chromosomal congression and segregation during real time cell division.

Erscheint lt. Verlag	23.12.2011
Sprache	englisch
Maße	148 x 210 mm
Gewicht	100 g
Themenwelt	Naturwissenschaften ► Chemie ► Organische Chemie
Schlagworte	er-alpha • hpip • Role
ISBN-10	3-656-07884-X / 365607884X
ISBN-13	978-3-656-07884-5 / 9783656078845
Zustand	Neuware