Bioinorganic Chemistry (eBook)

A Practical Course

Nils Metzler-Nolte, Ulrich Schatzschneider (Autoren)

eBook Download: PDF

2009
147 Seiten
De Gruyter (Verlag)
978-3-11-021136-8 (ISBN)

Infos

This book presents a unique introduction into the field of bioinorganic chemistry through practical laboratory experiments. Topics include many aspects of modern bioinorganic chemistry such as model systems for metalloenzymes, biosensors, metal bioconjugates and metal-based drugs. Each chapter contains a brief introduction, followed by detailed experimental procedures, completed with all necessary background information for the student as well as their instructors.

• A valuable supplement to standard textbooks of inorganic and bioinorganic chemistry
• Essential for all instructors teaching laboratory courses in general and inorganic chemistry

Nils Metzler-Nolte, Ruhr University, Bochum, Germany; Ulrich Schatzschneider, Ruhr University, Bochum, Germany

Autor

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Nils Metzler-Nolte, Ruhr University, Bochum, Germany; Ulrich Schatzschneider, Ruhr University, Bochum, Germany

Inhalt

Preface and Acknowledgements 6
Table of Contents 8
1. Introduction 12
2. Small molecule activation and inactivation by metalloenzymes and their model compounds 18
3. Carbon monoxide and nitric oxide as small molecule messengers 30
4. Metallointercalators as DNA probes 42
5. DNA manipulation with metal complexes 60
6. Synthesis of metal-peptide bioconjugates 78
7. Preparation of metal-protein bioconjugates 98
8. Electrochemical investigation of metal complexes 112
9. Metal complexes with anti-proliferative activity 126
Glossary 144
Index 148

Rezensionen

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"This delightful book breaks new ground as it is the first lab manual devoted entirely to experiments in bioinorganic chemistry."
Richard S. Herrick in: Journal of Chemical Education 2010

"Ein sehr gutes Buch."
Siegfried Schindler in: Nachrichten aus der Chemie 5/2010

"Insgesamt ist das Buch sehr empfehlenswert für Lehrende und Lernende der bioanorganischen Chemie, wenn man das Thema nicht nur in einer Vorlesung oder einem Seminar erschöpfen will, sondern auch praktisch lehren und lernen möchte."
Axel Klein in: Angewandte Chemie 122/2010

Produkt-Details

• Erscheint lt. Verlag: 10.9.2009
• Zusatzinfo: 46 b/w ill., 5 b/w tbl.
• Verlagsort: Berlin/Boston
• Sprache: englisch
• Themenwelt: Naturwissenschaften ► Biologie
• Themenwelt: Naturwissenschaften ► Chemie ► Anorganische Chemie
• Themenwelt: Technik
• Schlagworte: Anorganische Chemie • Bioanorganische Chemie • Biochemischie • biochemistry • bioinorganic chemistry • Inorganic Chemistry • Laboratory Course • Laboratory course, biochemistry • Laboratory course, inorganic chemistry • Praktikum
• ISBN-10: 3-11-021136-X / 311021136X
• ISBN-13: 978-3-11-021136-8 / 9783110211368