Alzheimer Disease: The Changing View (eBook)

The Changing View

Katherine Bick, Robert Katzman (Autoren)

eBook Download: PDF

2000 | 1. Auflage
387 Seiten
Elsevier Science (Verlag)
978-0-08-052708-6 (ISBN)

Infos

This book details how 'Alzheimer Disease' went from being an obscure neurologic diagnosis to a household word. The words of those responsible for this revolution are the heart of this book. Dr. Robert Katzman and Dr. Katherine Bick, leaders in Alzheimer research and policy making, interview the people responsible for this awakening of public consciousness about AlzheimerDisease from 1960 to 1980. They speak with the scientists, public health officials, government regulators, and concerned relatives and activists responsible for taking this neurodegenerative disease out of the 'back wards' through the halls of Congress, and on to the front page. The reader will learn how the explosive increase in research funding and public awareness came about, how physicians and psychiatrists established diagnostic criteria, how drugs were developed that offer hope for sufferers, and how the Alzheimer's Association was born.* Written in the words of those responsible for the widespread recognition of this neurodegenerative disease* The authors are recognised as leaders in Alzheimer research and policy making

Robert Katzman, M.D., a member of the Institute of Medicine of the National Academy of Sciences, is the recipient of numerous scientific awards. He has enjoyed a long career as a physician, neuroscientist, and policy maker, serving on the faculty at Albert Einstein University in New York and currently at the University of California, San Diego. His research has centered on the epidemiology of aging and Alzheimer disease, and his seminal editorial in 1976 sparked the NIH to hold the first conference on the subject. Dr. Katzman has been a catalyst in the formation of the Alzheimer's Association.

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This book details how "e;Alzheimer Disease"e; went from being an obscure neurologic diagnosis to a household word. The words of those responsible for this revolution are the heart of this book. Dr. Robert Katzman and Dr. Katherine Bick, leaders in Alzheimer research and policy making, interview the people responsible for this awakening of public consciousness about AlzheimerDisease from 1960 to 1980. They speak with the scientists, public health officials, government regulators, and concerned relatives and activists responsible for taking this neurodegenerative disease out of the "e;back wards"e; through the halls of Congress, and on to the front page. The reader will learn how the explosive increase in research funding and public awareness came about, how physicians and psychiatrists established diagnostic criteria, how drugs were developed that offer hope for sufferers, and how the Alzheimer's Association was born.* Written in the words of those responsible for the widespread recognition of this neurodegenerative disease* The authors are recognised as leaders in Alzheimer research and policy making

Inhalt

Front Cover 1
Alzheimer Disease: The Changing View 4
Copyright Page 5
Contents 8
Preface 12
Chapter I. Setting the Stage 16
Chapter 2. The Pioneers 26
The Ultrastructure of AD 26
Cognitive Decline in the Elderly and AD Pathology — The First Prospective Study: Newcastle 61
Chapter 3. The Need For Care 112
The Impact on Families 112
Designing the First Special Care Unit 129
Chapter 4. Understanding the Biology of AD 142
Experimental Models 142
Genetics 165
Chapter 5. The Cholinergic Story: Hope for the Patient and Family 182
Clues and Chemical Leads: Scopolamine Impairs Cognition 182
The Loss of Cholinergic Markers in the AD Brain 194
Chapter 6. Improving the Accuracy of Diagnosis 226
Chapter 7. The Impact of AD and Society's Response 252
Demography 252
Public Health Impact 267
The National Institutes of Health Respond 287
The Rise of the Alzheimer's Association 327
Chapter 8. The Next Act 368
Index 394

Produkt-Details

• Erscheint lt. Verlag: 22.5.2000
• Sprache: englisch
• Themenwelt: Geisteswissenschaften ► Psychologie ► Klinische Psychologie
• Themenwelt: Medizin / Pharmazie ► Allgemeines / Lexika
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Geriatrie
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Neurologie
• Themenwelt: Studium ► Querschnittsbereiche ► Geschichte / Ethik der Medizin
• Themenwelt: Naturwissenschaften ► Biologie ► Humanbiologie
• Themenwelt: Naturwissenschaften ► Biologie ► Zoologie
• ISBN-10: 0-08-052708-6 / 0080527086
• ISBN-13: 978-0-08-052708-6 / 9780080527086