Brain Repair (eBook)
XII, 252 Seiten
Springer US (Verlag)
978-0-387-30128-0 (ISBN)
Brain Repair, addresses all relevant issues underlying the mechanisms of brain damage, brain plasticity and post-traumatic reorganisation after CNS lesions. This book is divided the three major sections that follow; cellular and molecular basis of brain repair, plasticity and reorganisation of neural networks, and experimental therapy strategies.
Brain Repair is written by high profile, international experts who describe in detail the newest results from basic research and highlight new model systems, techniques and therapy approaches. Based on a careful analysis of the cellular and molecular reaction patterns of the CNS to lesions, the contributions cover possibilities for endogenous reorganisation and repair as well as exciting new therapies emerging from basic research, some of which have already been introduced into the clinics. Thus, this book is unique in bridging the gap between basic and clinical research. It will be a valuable tool for all students, researchers and clinicians interested in understanding the brain's capacity to cope with lesions and interested in learning about emerging new therapy concepts.
Brain Repair, addresses all relevant issues underlying the mechanisms of brain damage, brain plasticity and post-traumatic reorganisation after CNS lesions. This book is divided the three major sections that follow; cellular and molecular basis of brain repair, plasticity and reorganisation of neural networks, and experimental therapy strategies.Brain Repair is written by high profile, international experts who describe in detail the newest results from basic research and highlight new model systems, techniques and therapy approaches. Based on a careful analysis of the cellular and molecular reaction patterns of the CNS to lesions, the contributions cover possibilities for endogenous reorganisation and repair as well as exciting new therapies emerging from basic research, some of which have already been introduced into the clinics. Thus, this book is unique in bridging the gap between basic and clinical research. It will be a valuable tool for all students, researchers and clinicians interested in understanding the brain's capacity to cope with lesions and interested in learning about emerging new therapy concepts.
PARTICIPANTS 6
CONTENTS 9
Cell Death in the Nervous System 13
The Glial Response to Injury and Its Role in the Inhibition of CNS Repair 23
DSD-1 -Proteoglycan/Phosphacan and Receptor Protein Tyrosine Phosphatase-Beta Isoforms during Development and Regeneration of Neural Tissues 37
Regeneration Failure in the CNS: Cellular and Molecular Mechanisms 66
The Role of lonotropic Purinergic Receptors (P2X) in Mediating Plasticity Responses in the Central Nervous System 89
Lesion-Induced Axonal Sprouting in die Central Nervous System 113
A Kinase with a Vision: Role of ERK in the Synaptic Plasticity of the Visual Cortex 134
Attempts to Restore Visual Function after Optic Nerve Damage in Adult Mammals 145
Brain Repair: Experimental Treatment Strategies, Neuroprotective and Repair Strategies in the Lesioned Adult CNS 160
Neuroprotection by cAMP: Another Brick in the Wall 176
The Collagenous Wound Healing Scar in the Injured Central Nervous System Inhibits Axonal Regeneration 189
Role of Endogenous Neural Stem Cells in Neurological Disease and Brain Repair 203
Transplantation in Parkinsons Disease: The Future Looks Bright 233
Index 261
| Erscheint lt. Verlag | 6.3.2007 |
|---|---|
| Reihe/Serie | Advances in Experimental Medicine and Biology | Advances in Experimental Medicine and Biology |
| Zusatzinfo | XII, 252 p. |
| Verlagsort | New York |
| Sprache | englisch |
| Themenwelt | Medizin / Pharmazie ► Allgemeines / Lexika |
| Medizinische Fachgebiete ► Chirurgie ► Neurochirurgie | |
| Medizin / Pharmazie ► Medizinische Fachgebiete ► Neurologie | |
| Studium ► 2. Studienabschnitt (Klinik) ► Pathologie | |
| Naturwissenschaften ► Biologie ► Humanbiologie | |
| Naturwissenschaften ► Biologie ► Zoologie | |
| Schlagworte | brain • Cell • cell death • central nervous system • CNS • Cortex • Death • nervous system • Neural networks • Neuroprotection • Parkinson • Protein • receptor • tissue • Trauma |
| ISBN-10 | 0-387-30128-3 / 0387301283 |
| ISBN-13 | 978-0-387-30128-0 / 9780387301280 |
| Haben Sie eine Frage zum Produkt? |
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