Arrhythmogenic RV Cardiomyopathy/Dysplasia (eBook)

Recent Advances

Frank I. Marcus, Andrea Nava, Gaetano Thiene (Herausgeber)

eBook Download: PDF

2007 | 2007
XIII, 217 Seiten
Springer Italia (Verlag)
978-88-470-0490-0 (ISBN)

Infos

This book covers all aspects (biological, pathological, genetic, clinical and therapeutical) of arrhythmogenic right ventricular cardiomyopathy/dysplasia, a recent cardiomyopathy which represents a very high risk of sudden death in the young and in the athletes. This monograph gathers the results of a five-year research program on ARVC/D which allowed the discovery of 5 disease-causing genes, thus opening new avenues for the early identification of affected patients.

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This book covers all the recent research highlights of arrhythmogenic right ventr- ular cardiomyopathy/dysplasia (ARVC/D), a recently discovered heart muscle d- ease which is a major threat to the life of affected young people. It summarizes ne- ly 25 years of investigation on the etiology, genetics, pathology, clinical features, - agnosis, and treatment of ARVC/D. In particular, a 5-year research program supported by grants from both the European Community and the National Heart, Lung and Blood Institutes has contributed to the discovery of seven disease-causing genes, thus opening new avenues for the early identification of affected patients and prevention of sudden death. A Workshop was held in Venice, Italy, October 3, 2005, as part of the Venice - rhythmia Meeting, where the European and American investigators presented and discussed several major achievements which are now reported in this book.As a - sult of these coordinated efforts, great advances have been made in the recognition and understanding of the disease, which are summarized in this book.

Inhalt

Introduction: Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia Clarified.- Advances in Genetics: Dominant Forms.- Advances in Genetics: Recessive Forms.- Genotype-Phenotype Correlations.- Autopsy and Endomyocardial Biopsy Findings.- Cell Adhesion Pathology.- Ultrastructural Substrates.- Transgenic Animal Models.- Spontaneous Animal Models.- Possible Causative or Contributing Role of Viruses.- Diagnosis: Task Force Criteria including Modifications for Family Members.- Strengths and Weaknesses of the Task Force Criteria — Proposed Modifications.- Idiopathic Right Ventricular Outflow Tract Tachycardia.- Electrocardiographic Manifestations.- Echocardiography.- MR and CT Imaging.- Diagnostic Role of Angiography.- Electrophysiologic Study including Electroanatomic Mapping.- Risk Stratification and Antiarrhythmic Drug Therapy.- Catheter Ablation of Ventricular Tachycardia.- The Role of the Implantable Cardiac Defibrillator in the Management.- Management of Heart Failure.- Sudden Death in Young Athletes.

Produkt-Details

• Erscheint lt. Verlag: 5.11.2007
• Zusatzinfo: XIII, 217 p.
• Verlagsort: Milano
• Sprache: englisch
• Themenwelt: Medizin / Pharmazie ► Allgemeines / Lexika
• Themenwelt: Medizinische Fachgebiete ► Innere Medizin ► Kardiologie / Angiologie
• Themenwelt: Medizin / Pharmazie ► Pflege
• Themenwelt: Studium ► 1. Studienabschnitt (Vorklinik) ► Physiologie
• Themenwelt: Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik
• Themenwelt: Studium ► 2. Studienabschnitt (Klinik) ► Pathologie
• Themenwelt: Naturwissenschaften ► Biologie
• Themenwelt: Technik
• Schlagworte: Ablation • Angiography • biopsy • Cell • Echocardiography • genes • Genetics • heart • Human genetics • Radiology
• ISBN-10: 88-470-0490-X / 884700490X
• ISBN-13: 978-88-470-0490-0 / 9788847004900