Natural Killer Cells (eBook)

At the Forefront of Modern Immunology

Jacques Zimmer (Herausgeber)

eBook Download: PDF

2010
IX, 428 Seiten
Springer Berlin (Verlag)
978-3-642-02309-5 (ISBN)

Infos

Natural killer (NK) cells have been at the forefront of immunology for two decades. During that time, a great amount of information about these cells has been obtained. They are important in antiinfectious and antitumoral defense and shape the adaptive immune response. In addition, they can act as immunoregulatory cells. In recent years, the therapeutic potential of NK cells in cancer immunotherapy has become increasingly evident. This book describes in detail current knowledge about NK cells and covers a broad range of NK cell-related topics, including those that are not frequently reviewed, e.g. NK cells and allergy or NK cells and skin diseases.

Inhalt

Preface 5
Contents 6
Natural Killer Cells: Deciphering Their Role, Diversity and Functions 9
Dissecting Human NK Cell Development and Differentiation 47
Diversity of KIR Genes, Alleles and Haplotypes 70
NK Cell Education and CIS Interaction Between Inhibitory NK Cell Receptors and Their Ligands 99
Trogocytosis and NK Cells in Mouse and Man 115
Virus Interactions with NK Cell Receptors 130
The Role of NK Cells in Bacterial Infections 158
NK Cells and Autoimmunity 181
NK Cells and Allergy 195
Natural Killer Cells and Their Role in Hematopoietic Stem Cell Transplantation 203
NK Cells, NKT Cells, and KIR in Solid Organ Transplantation 224
NK Cells in Autoimmune and Inflammatory Diseases 243
Natural Killer Cells and the Skin 257
NK Cells in Oncology 269
The Role of KIR in Disease 277
Interactions Between NK Cells and Dendritic Cells 301
Modulation of T Cell-Mediated Immune Responses by Natural Killer Cells 316
Interactions Between NK Cells and Regulatory T Cells 329
Interactions Between B Lymphocytes and NK Cells: An Update 344
The Regulatory Natural Killer Cells 368
NK Cells and Microarrays 389
Natural Killer Cells in the Treatment of Human Cancer 403
Index 420

Produkt-Details

• Erscheint lt. Verlag: 12.1.2010
• Zusatzinfo: IX, 428 p.
• Verlagsort: Berlin
• Sprache: englisch
• Themenwelt: Studium ► Querschnittsbereiche ► Infektiologie / Immunologie
• Themenwelt: Naturwissenschaften ► Biologie
• Themenwelt: Technik
• Schlagworte: autoimmunity • Bacteria • Cells • Diseases • hematopoietic stem cell transplantation • immune response • immunity • immunology • immunotherapy • Infection • Infections • Lymphocytes • natural killer cells • NK cells • stem cell transplantation • Transplantation • Virus
• ISBN-10: 3-642-02309-6 / 3642023096
• ISBN-13: 978-3-642-02309-5 / 9783642023095