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Protein Engineering for Therapeutics, Part A -

Protein Engineering for Therapeutics, Part A

Buch | Hardcover
392 Seiten
2012
Academic Press Inc (Verlag)
978-0-12-416039-2 (ISBN)
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Suitable for academics, researchers and students alike, this book looks at Protein Engineering for Therapeutics. It covers subjects such as Antibodies, Protein conjugates, Peptides, Enzymes and Scaffolds.
This volume of Methods in Enzymology looks at Protein Engineering for Therapeutics. The chapters provide an invaluable resource for academics, researchers and students alike. With an international board of authors, this volume is split into sections that cover subjects such as Antibodies, Protein conjugates, Peptides, Enzymes and Scaffolds

Simplified Synthetic Antibody Libraries
Generation of Dual Variable Domain Immunoglobulin Molecules for Dual-specific Targeting


Discovery of internalizing antibodies to tumor antigens from phage libraries


Optimizing properties of anti-receptor antibodies using kinetic computational models and experiments


Cell-specific siRNA delivery by peptides and antibodies


Conjugation of Anticancer Drugs Through Endogenous Monoclonal Antibody Cysteine Residues


Building and characterizing antibody-targeted lipidic nanotherapeutics


Cell-Targeting Fusion Constructs Containing Recombinant Gelonin


Stapled Peptides for Intracellular Drug Targets


Mapping of vascular zip codes by phage display


Engineering cyclic peptide toxins


Peptide Discovery using Bacterial Display and Flow Cytometry


Oral enzyme therapy for celiac sprue


Rational Design and Evaluation of Mammalian Ribonuclease Cytotoxins


Engineering Reduced-Immunogenicity Enzymes for Amino Acid Depletion Therapy in Cancer


Designed Ankyrin Repeat Proteins (DARPins): From research to therapy


Target-binding proteins based on the tenth human fibronectin type III domain (10Fn3)


Anticalins: small engineered binding proteins based on the lipocalin scaffold


T Cell Receptor Engineering


Engineering Knottins as Novel Binding Agents


Re-Engineering Biopharmaceuticals for Targeted Delivery Across the Blood-Brain Barrier


Practical Theoretic Guidance for the Design of Tumor Targeting Agents


Fusions of elastin-like polypeptides to pharmaceutical proteins


Engineering and Identifying Supercharged Proteins for Macromolecule Delivery into Mammalian Cells

Erscheint lt. Verlag 23.2.2012
Reihe/Serie Methods in Enzymology
Verlagsort San Diego
Sprache englisch
Maße 152 x 229 mm
Gewicht 750 g
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Pharmakologie / Pharmakotherapie
Naturwissenschaften Biologie Biochemie
Technik
ISBN-10 0-12-416039-5 / 0124160395
ISBN-13 978-0-12-416039-2 / 9780124160392
Zustand Neuware
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