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DESIGN, SYNTHESIS AND FUSION ACTIVITY OF PNA/PEPTIDE HYBRIDS AS SNARE PROTEIN MODELS

DESIGN, SYNTHESIS AND FUSION ACTIVITY OF PNA/PEPTIDE HYBRIDS AS SNARE PROTEIN MODELS

Buch | Softcover
2011
Books on Demand (Verlag)
978-3-8423-7461-4 (ISBN)
CHF 26,60 inkl. MwSt
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In this study, the novel simplified SNARE-mimicking systems consisting of TMD/linker segments of the natural membrane-bound SNARE proteins (syntaxin-1A and synaptobrevin 2) and peptide nucleic acid (PNA) recognition motifs were designed and synthesized. The synthesized PNA/TMD hybrids were shown to efficiently induce vesicle fusion.

Antonina Lygina was born in Krasnodar, Russia in 1985. She studied chemistry at the M. V. Lomonosov Moscow State University in 2001-2006. Later she carried out her doctoral research in the group of Prof. Ulf Diederichsen (Göttingen, Germany) and obtained her doctor degree ("summa cum laude") in 2011.

Sprache englisch
Gewicht 223 g
Einbandart Paperback
Themenwelt Naturwissenschaften Chemie Organische Chemie
ISBN-10 3-8423-7461-5 / 3842374615
ISBN-13 978-3-8423-7461-4 / 9783842374614
Zustand Neuware
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