DESIGN, SYNTHESIS AND FUSION ACTIVITY OF PNA/PEPTIDE HYBRIDS AS SNARE PROTEIN MODELS

Buch | Softcover

2011
Books on Demand (Verlag)
978-3-8423-7461-4 (ISBN)

Titel ist leider vergriffen;
keine Neuauflage

Artikel merken

In this study, the novel simplified SNARE-mimicking systems consisting of TMD/linker segments of the natural membrane-bound SNARE proteins (syntaxin-1A and synaptobrevin 2) and peptide nucleic acid (PNA) recognition motifs were designed and synthesized. The synthesized PNA/TMD hybrids were shown to efficiently induce vesicle fusion.

Antonina Lygina was born in Krasnodar, Russia in 1985. She studied chemistry at the M. V. Lomonosov Moscow State University in 2001-2006. Later she carried out her doctoral research in the group of Prof. Ulf Diederichsen (Göttingen, Germany) and obtained her doctor degree ("summa cum laude") in 2011.

Sprache	englisch
Gewicht	223 g
Einbandart	Paperback
Themenwelt	Naturwissenschaften ► Chemie ► Organische Chemie
ISBN-10	3-8423-7461-5 / 3842374615
ISBN-13	978-3-8423-7461-4 / 9783842374614
Zustand	Neuware