Handbook of Harnessing Biomaterials in Nanomedicine

Preparation, Toxicity, and Applications

Dan Peer (Herausgeber)

Buch | Hardcover

424 Seiten

2012
Pan Stanford Publishing Pte Ltd (Verlag)
978-981-4316-46-0 (ISBN)

Infos

This book concentrates on the use of biomaterials in nanomedicine. The areas of focus include drug delivery by polymers , lipids and carbohydrates for the delivery of small molecules, RNA interference, and proteins; the use of nano-proteins such as antibodies and peptides as targeting agents for therapeutics and diagnosis; The use of nanocarrier-based biomaterials for manipulation of stem cells; different aspects of toxicity of nanocarriers (the immune response, liver toxicity, and many more); and success stories of biomaterials that have reached the clinics. The book comprises theoretical and experimental analysis of various biomaterials that are used in nanomedicine, research methods and preparation techniques, and several promising applications.

Autor

Dan Peer is a principal investigator and a senior lecturer and leads an NIH-funded laboratory at Tel Aviv University, Israel. Dan completed his education in biochemistry and biophysics from Tel Aviv University, Israel. From January 2005 to August 2008, he worked at Harvard Medical School. He joined the Department of Cell Research and Immunology, in the Faculty of life sciences at Tel Aviv University in September 2008 to establish the laboratory of nanomedicine. Dan’s research was between the first to demonstrate systemic delivery of RNAi using targeted nano-carriers to the immune system and the first to utilize RNAi for in vivo validation of new drug targets within the immune system. His work was published in premier scientific journals such as Science, Nature Nanotechnology, and PNAS. He is the editor and author of several books in the field of nanomedicine, an associate editor of Journal of Biomedical Nanotechnology, and Frontiers in Biotechnology and Drug Delivery, and on the editorial board of the journals Nanotechnology and Journal of Controlled Release. Dan has received more than 20 awards and honors.

Inhalt

Biomaterial-Based Particulate Drug Carriers. Single-Chain Polymer Nanoparticles for Application in Nanomedicine. Polyethylene Glycol Polyester Block Co-Polymers: Biocompatible Carriers for Nanoparticulate Drug Delivery. Recent Progress in Polymer Therapeutics as Nanomedicines. Polysaccharides as Nanomaterials for Therapeutics. RNAi as New Class of Nanomedicines. Novel RNA Interference (RNAi)-Based Nanomedicines for Treating Viral Infections. Detection and Description of Tissue Disease: Advances in the Use of Nanomedicine for Medical Imaging. Image-Based High-Content Analysis, Stem Cells and Nanomedicines: A Novel Strategy for Drug Discovery. Wrong Resemblance? Role of the Immune System in the Biocompatibility of Nanostructured Materials. Complement Activation, Immunogenicity and Immune Suppression as Potential Side Effects of Liposomes. The Story of DOXIL — A Personal Account.

Produkt-Details

• Zusatzinfo: 15 Illustrations, color; 30 Illustrations, black and white
• Verlagsort: Singapore
• Sprache: englisch
• Maße: 152 x 229 mm
• Gewicht: 703 g
• Themenwelt: Medizin / Pharmazie ► Physiotherapie / Ergotherapie ► Orthopädie
• Themenwelt: Naturwissenschaften ► Biologie
• Themenwelt: Technik ► Maschinenbau
• Themenwelt: Technik ► Medizintechnik
• Themenwelt: Technik ► Umwelttechnik / Biotechnologie
• ISBN-10: 981-4316-46-6 / 9814316466
• ISBN-13: 978-981-4316-46-0 / 9789814316460
• Zustand: Neuware