Stereotaxic and Chemoarchitectural Atlas of the Brain of the Common Marmoset (Callithrix jacchus)

Craig D. Hardman, Ken W. S. Ashwell (Autoren)

Buch | Hardcover

520 Seiten

2012
Crc Press Inc (Verlag)
978-1-4398-3778-8 (ISBN)

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Developing better therapies for neurological conditions such as Parkinson’s and Alzheimer’s diseases remains an enduring problem for 21st century medicine. The testing of novel therapies will continue to require a robust experimental animal model. The marmoset is an ideal animal model for modern neurological research because of the species’ convenient body size, ease of handling, and the fundamental similarity of its neuroanatomy to the human brain.

The Stereotaxic and Chemoarchitectural Atlas of the Brain of the Common Marmoset (Callithrix jacchus) is the most detailed atlas of the marmoset brain available. An essential tool for researchers developing more effective therapies for disabling and debilitating neurological disorders, the book contains:

Fully delineated, high-quality (400x magnification) images of Nissl-stained, acetylcholinesterase histochemically-stained and parvalbumin, calbindin and neurofilament immunohistochemically-stained coronal and sagittal sections, as well as structural magnetic resonance images (MRI) for direct comparisons
Line diagrams with delineations of all cortical and subcortical structures, with grid overlays so the precise position of each structure can be located stereotaxically relative to the interaural line and infraorbital margin
Quantitative data regarding volume and cell number of many of the structures delineated in the atlas, regularly updated on an accompanying website
Standard nomenclature widely used in the Paxinos group of atlases, allowing users to compare and contrast homologous nuclei in different species using the major available atlases

The book combines modern imaging (MRI) with an accurate stereotaxic and chemoarchitectonic section atlas, making the fullest use of available technologies. The downloadable resources include all the images in full color. Designed by publishing neuroanatomists, this book/downloadable resources will be a cornerstone in marmoset brain research for years to come.

Dr. Craig Hardman is a Lecturer within the Department of Anatomy, School of Medical Sciences at the University of New South Wales, Australia. Professor Ken WS Ashwell is a Professor within the Department of Anatomy, School of Medical Sciences at the University of New South Wales, Australia.

Introduction: Ecology, Behavior and Evolution of the Common Marmoset, The Marmoset in Neuroscience Research. Key Features of this Book. Animals and Ethical Considerations. Methods: MRI, Perfusion and Tissue Processing. Imaging, Principles of Delineation and Abbreviation. Quantitation of Volumes and Neuronal Populations of Motor Nuclei. Bases for Delineation of Specific Regions and Nuclei. References. Named structures and abbreviations. Index of atlas plates. Atlas plates.

Erscheint lt. Verlag	1.2.2012
Zusatzinfo	2 Tables, black and white; 457 Illustrations, color; 457 Illustrations, black and white
Verlagsort	Bosa Roca
Sprache	englisch
Maße	210 x 280 mm
Gewicht	1120 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Neurologie
	Studium ► 2. Studienabschnitt (Klinik) ► Pharmakologie / Toxikologie
	Naturwissenschaften ► Biologie ► Biochemie
	Naturwissenschaften ► Biologie ► Humanbiologie
	Naturwissenschaften ► Biologie ► Zoologie
ISBN-10	1-4398-3778-3 / 1439837783
ISBN-13	978-1-4398-3778-8 / 9781439837788
Zustand	Neuware