Freeze–Drying 2e
Seiten
2007
Wiley-VCH Verlag GmbH (Hersteller)
978-3-527-61248-2 (ISBN)
Wiley-VCH Verlag GmbH (Hersteller)
978-3-527-61248-2 (ISBN)
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Many modern pharmaceutical and biological products, e.g. blood derivatives, vaccines, cytostatic drugs, antibiotics, bacteria cultures but also consumer goods such as soluble coffee are freeze-dried to transform perishable substances into a form that can be stored and reconstituted to their almost original state without loss of quality.
The book describes the up-to-date fundamentals of freeze-drying, not just presenting the process in all its seven steps theoretically, but explaining it with many practical examples. Many years of experience in freeze-drying allow the authors to supply valuable criteria for the selection of laboratory, pilot and production plants, discussing the advantages, drawbacks and limitations of different plant designs.
In this second, completely revised edition, process and plant automation are introduced in a separate section and methods to transfer pilot plant qualifications and process data to production are presented. The guidelines for process and plant evaluation and qualifications have been updated and enlarged. Trouble shooting is concentrated in a section of its own and literature has been updated with 100 new quotations to include references as recent as 2002, and 100 new tables and figures have been added.
The book describes the up-to-date fundamentals of freeze-drying, not just presenting the process in all its seven steps theoretically, but explaining it with many practical examples. Many years of experience in freeze-drying allow the authors to supply valuable criteria for the selection of laboratory, pilot and production plants, discussing the advantages, drawbacks and limitations of different plant designs.
In this second, completely revised edition, process and plant automation are introduced in a separate section and methods to transfer pilot plant qualifications and process data to production are presented. The guidelines for process and plant evaluation and qualifications have been updated and enlarged. Trouble shooting is concentrated in a section of its own and literature has been updated with 100 new quotations to include references as recent as 2002, and 100 new tables and figures have been added.
Georg-Wilhelm Oetjen is the editor of Freeze-Drying, published by Wiley. Peter Haseley is an independent consultant for lyophilization technology, including process and cycle development with an expertise in freeze-drying of ODT, the development and design study for a semi-continuous working lyophilization plants, the transfer of Freeze-Drying cycles from an Usifroid plant to a Telstar plant, cycle development and process optimization and the standardization of projects for costs reduction and fast track component production.
| Erscheint lt. Verlag | 25.10.2007 |
|---|---|
| Verlagsort | Weinheim |
| Sprache | englisch |
| Maße | 186 x 246 mm |
| Gewicht | 952 g |
| Themenwelt | Naturwissenschaften ► Chemie ► Technische Chemie |
| Technik | |
| ISBN-10 | 3-527-61248-3 / 3527612483 |
| ISBN-13 | 978-3-527-61248-2 / 9783527612482 |
| Zustand | Neuware |
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