Membrane Transporters as Drug Targets

Gordon L. Amidon, Wolfgang Sadée (Herausgeber)

Buch | Hardcover

530 Seiten

1999
Kluwer Academic/Plenum Publishers (Verlag)
978-0-306-46094-4 (ISBN)

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Because progress in the field of transporters has been extraordinary, this volume will focus on recent advances in our understanding of the structure, function, physiology, and molecular biology of membrane transporters. There will be an emphasis on transporters as molecular targets for drug delivery and disposition in the body.

Overview of Membrane Transport.- Classification of Membrane Transporters.- Drug Transport and Targeting.- The Molecular Basis for Hepatobiliary Transport of Organic Cations and Organic Anions.- Affinity of Drugs to the Different Renal Transporters for Organic Anions and Organic Cations.- Drug Disposition and Targeting.- The Mammalian Facilitative Glucose Transporter (GLUT) Family.- Cationic Amino Acid Transporters (CATs).- Electrophysiological Analysis of Renal Na+-Coupled Divalent Anion Transporters.- Dipeptide Transporters.- Antigenic Peptide Transporter.- Nucleoside Transporters of Mammalian Cells.- Multidrug-Resistance Transporters.- Transporters for Bile Acids and Organic Anions.- Molecular and Functional Characteristics of Cloned Human Organic Cation Transporters.- Organic Anion Transporters.- Vitamin B12 Transporters.

Reihe/Serie	Pharmaceutical Biotechnology ; 12
Zusatzinfo	XXV, 530 p.
Verlagsort	New York
Sprache	englisch
Maße	155 x 235 mm
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
	Medizin / Pharmazie ► Pharmazie
	Naturwissenschaften ► Biologie ► Biochemie
ISBN-10	0-306-46094-7 / 0306460947
ISBN-13	978-0-306-46094-4 / 9780306460944
Zustand	Neuware