Beta Cells
Nova Science Publishers Inc (Verlag)
978-1-61761-212-1 (ISBN)
Beta cells or ss-cells, are a type of cell in the pancreas in areas called the islets of Langerhans. They make up 65-80% of the cells in the islets. Pancreatic B-cell is the only cell type that produces insulin to regulate glucose metabolism in the body. The insufficiency of insulin-producing B-cells results in dysregulation of blood glucose control, termed as type 1 diabetes. This book presents current research from across the globe in the study of Beta-cells, including the induction of pancreatic cancer cell death by elevated concentrations of extracellular zinc; the role of Rab GTPases and their effectors in the insulin secretory pathway of the pancreatic beta cell; In vivo reprogramming of pancreatic A-cells into B-like cells; and the role of glucocortoids, exercise and glucolipotoxicity with regard to stress and pancreatic B-cell function.
Stress & Pancreatic ss Cell Function: Role of Glucocortoids, Exercise & Glucolipotoxicity; The Synergistic Effect of ss Cell Replacement & Immunotherapy on the Treatment of Type 1 Diabetes; Antagonizing the Endocannabinoid Pathway Prevents the Development of Diabetes & ss Cell Dysfunction in Zucker Diabetic Fatty Rats; Diabetes Mellitus: An Opportunity for Therapy with Regenerative Medicine?; Behind Beta Cell Glucotoxicity: A Pivotal Role of Glycoxidative Damage?; Induction of Pancreatic Cancer Cell Death by Elevated Concentrations of Extracellular Zinc; Rab GTPases Control Membrane Recycling in the Pancreatic Beta Cell; In Vivo Reprogramming of Pancreatic ?-cells into ss-like Cells; Studies of Toxin Resistant Beta-Cells: Lessons for the Chemotherapy?; Renin-Angiotensin System & Diabetes.
| Zusatzinfo | Illustrations, unspecified |
|---|---|
| Verlagsort | New York |
| Sprache | englisch |
| Maße | 260 x 180 mm |
| Gewicht | 526 g |
| Themenwelt | Studium ► 1. Studienabschnitt (Vorklinik) ► Physiologie |
| Naturwissenschaften ► Biologie ► Zellbiologie | |
| ISBN-10 | 1-61761-212-X / 161761212X |
| ISBN-13 | 978-1-61761-212-1 / 9781617612121 |
| Zustand | Neuware |
| Haben Sie eine Frage zum Produkt? |
aus dem Bereich
