Microglia in the Regenerating and Degenerating Central Nervous System

Buch | Softcover

326 Seiten

2011 | Softcover reprint of hardcover 1st ed. 2002
Springer-Verlag New York Inc.
978-1-4419-2944-0 (ISBN)

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The study of microglial cells has recently gained importance for those researching degeneration and regeneration. Microglia in the regenerating and degenerating CNS supports the assertion that understanding microglial biology could perhaps be pivotal for unraveling the pathogenetic mechanisms that underlie Alzheimer's disease, In addition, microglia are also critical for understanding the sequelae of traumatic brain and spinal cord injury, and for the important post-traumatic repair processes. This book gives an up to date account of the role of microglia in degeneration and regeneration of the nervous system and reviews their cell function and physiology.

Foreword

Section I. Microglial Physiology
Physiology and Pathophysiology of Microglial Cell Function by Wolfgang J. Streit
Roles of Microglia in the Developing Visual System by Julio Navascues, Miguel A. Cuadros, Ruth Calvente, Jose L. Marin-Teva
Microglial Ion Channels by Claudia Eder
Calcium Signaling in Microglial Cells by Thomas Muller
Microglia as a Source and Target of Cytokine Activities in the Brain by Uwe-Karsten Hanisch
Section II. Acute CNS Injury and Repair
Microglia and Macrophage Responses in Cerebral Ischemia by Guido Stoll, Sebastian Jander, Michael Schroeter
Role of Microglia and Macrophages in Secondary Injury of the Traumatized Spinal Cord: Troublemakers or Scapegoats? by Phillip G. Popovich
Microglial Response in the Axotomized Facial Motor Nucleus by Gennadij Raivich
Neuroprotective Roles of Microglia in the Central Nervous System by Kazuyuki Nakajima, Shinichi Kohsaka
Influences of Activated Microglia/Brain Macrophages on Spinal Cord Injury and Regeneration by Alexander G. Rabchevsky
Opportunities for Axon Repair in the CNS: Use of Microglia and Biopolymer Compositions by Joshua B. Stopek, Wolfgang J. Streit, Eugene P. Goldberg
Section III. Alzheimer's Disease and Aging
Beta Amyloid Protein Clearance and Microglial Activiation by Sally A. Frautschy, Greg M. Cole, March D. Ard
Microglia and Aging in the Brain by Caleb E. Finch, Todd E. Morgan, Irina Rozovsky, Zhong Xie, Richard Weindruch, Tomas Prolla

Index

Zusatzinfo	46 black & white illustrations, 7 black & white tables
Verlagsort	New York, NY
Sprache	englisch
Maße	155 x 235 mm
Gewicht	497 g
Einbandart	Paperback
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Neurologie
	Studium ► 1. Studienabschnitt (Vorklinik) ► Physiologie
	Naturwissenschaften ► Biologie ► Biochemie
	Naturwissenschaften ► Biologie ► Humanbiologie
	Naturwissenschaften ► Biologie ► Zoologie
ISBN-10	1-4419-2944-4 / 1441929444
ISBN-13	978-1-4419-2944-0 / 9781441929440
Zustand	Neuware