Erythropoietin – Blood, Brain and Beyond
Wiley-VCH Verlag GmbH (Hersteller)
978-3-527-60238-4 (ISBN)
- Keine Verlagsinformationen verfügbar
- Artikel merken
The use of Epo in medical practice is increasing constantly. It has revolutionized how we think of blood transfusion in medicine and surgery. Moreover, it has become widely known to scientists, physicians, biotech and pharmaceutical executives and the general public. Additionally, the past ten years have seen important advances in our knowledge and understanding of its action both within and outside of the hematopoietic system. Until now, there has been no single source that contains up-to-date information on Epo addressing the array of subjects that this book presents. The book covers all aspects from developmental biology to specific topics such as medical applications of recombinant Epo, receptor biology, mechanisms of Epo activity, structure/activity relationship, disease states and important actions on non-hematopoietic organs and tissues, including the central nervous system, heart, gastrointestinal tract, reproductive organs and endothelium.
Dr. Arthur Sytkowski received his Doctor of Medicine from the Medical College of Wisconsin and worked as a Research Associate in the Laboratory of Biochemical Genetics, National Heart, Lung and Blood Institute (NHLBI), NIH, Bethesda. In 1977, he joined Harvard Medical School, and established his research on the structure and function of human erythropoietin. Current research interests include therapeutic protein engineering, the control of blood cell differentiation, mechanisms of neoplasia, biological effects of microgravity, ligand/receptor biochemistry, growth factor signal transduction, gene regulation and cancer chemoprevention.
Preface. 1. Introduction and History. 2. Developmental Biology of Erythropoiesis and Erythropoietin Production. 3. Regulation of the Erythropoietin Gene: A Paradigm for Hypoxia dependent Genes. 4. Physiology and Metabolism of Erythropoietin. 5. Biochemistry and Protein Structure. 6. Receptor Biology and Signal Transduction. 7. Clinical Disorders of Erythropoietin and its Receptor. 8. Recombinant Erythropoietin and the Treatment of Anemia. 9. Functions of Erythropoietin Outside of Hematopoiesis. 10. Erythropoietin and Sport. 11. The Future of Erythropoietin. Subject Index.
| Erscheint lt. Verlag | 28.1.2005 |
|---|---|
| Verlagsort | Weinheim |
| Sprache | englisch |
| Maße | 130 x 250 mm |
| Gewicht | 666 g |
| Themenwelt | Medizin / Pharmazie ► Allgemeines / Lexika |
| Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie | |
| Naturwissenschaften ► Biologie | |
| ISBN-10 | 3-527-60238-0 / 3527602380 |
| ISBN-13 | 978-3-527-60238-4 / 9783527602384 |
| Zustand | Neuware |
| Haben Sie eine Frage zum Produkt? |
aus dem Bereich
