Biocatalysis – Fundamentals and Applications
Wiley-VCH Verlag GmbH (Hersteller)
978-3-527-60236-0 (ISBN)
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This book not only covers reactions, products and processes with and from biological catalysts, but also the process of designing and improving such biocatalysts, taking into account all recent insights. A unique feature is that the fields of organic chemistry, biology and bioengineering receive equal attention, such that practitioners and students from all three areas are addressed.
Andreas S. Bommarius obtained his diploma in Chemistry from the Technical Universtiy in Munich, Germany, and, in 1989, his PhD in Chemical Engineering from Massachusetts Institute of Technology (MIT) in Cambridge, MA,USA. In 1990, he joined Degussa as head of the Biocatalysis Laboratory and pilot plant. Since 2000 he is affiliated at Georgia Institute of Technology in Atlanta, Georgia, USA, as professor in the Schools of Chemical and Biomolecular Engineering and Chemistry and Biochemistry. His main research interests are novel redox enzyme systems, stability of protein biocatalysts, as well as novel catalysts through directed evolution. Bettina R. Riebel obtained her diploma in Biology at the University of Cologne, Germany, and her PhD in Biochemistry at the University of Dusseldorf, Germany. She then occupied postdoctoral associate positions with Roche Diagnostics (then Boehringer Mannheim) in Penzberg and at the Research Center Julich. As of 2000, she is part of the Institute of Pathology in the School of Medicine at Emory University in Atlanta, Georgia, USA, where her main research interests are in host pathogen rela tionships, and specifically in tyrosine kinases and cell signaling.
PART I: FUNDAMENTALS AND BASIC TOOLS Position of biocatalysis within biotechnology Characterization of a (bio )catalyst Isolation and preparation of microorganisms Molecular biology tools for biocatalysis Enzyme reaction engineering Applications of enzymes as bulk actives: detergents, textile, pulp and paper, animal feed Applications of enzymes as catalyst:Chemicals, fine chemicals, food, pharmaceuticals PART II: ADVANCED TOOLS Biotechnological processing steps for enzyme manufacture Methods for the investigation of proteins Protein Engineering Applications of recombinant DNA technology: Directed evolution Biocatalysis in non conventional media Pharmaceutical applications of biocatalysis Bioinformatics Systems biology for biocatalysis PART III: APPLICATIONS Evolution of biocatalytic function Stability of proteins Artificial enzymes Design of biocatalytic processes Comparison of biocatalysts with homogeneous and heterogeneous chemical catalysts New functions through application of bioinformatics Genomics and proteomics: applications
Erscheint lt. Verlag | 28.1.2005 |
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Verlagsort | Weinheim |
Sprache | englisch |
Maße | 130 x 250 mm |
Gewicht | 666 g |
Themenwelt | Naturwissenschaften ► Biologie ► Biochemie |
Naturwissenschaften ► Chemie ► Physikalische Chemie | |
Technik ► Umwelttechnik / Biotechnologie | |
ISBN-10 | 3-527-60236-4 / 3527602364 |
ISBN-13 | 978-3-527-60236-0 / 9783527602360 |
Zustand | Neuware |
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