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Quaternary Stereocenters – Challenges and Solutions for Organic Synthesis

J Christoffers (Autor)

Software / Digital Media
359 Seiten
2006
Wiley-VCH Verlag GmbH (Hersteller)
978-3-527-60685-6 (ISBN)
CHF 279,95 inkl. MwSt
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Covers the quaternary stereocenters found in a range of important and useful molecules in pharmaceutical and medicinal applications, as well as in thousands of natural products. This book provides the know how chemists need to synthesize important drugs.
Filling the gap in the literature, this book presents everything there is to know about this topic. By comprehensively covering the quaternary stereocenters found in a range of important and useful molecules in pharmaceutical and medicinal applications, as well as in thousands of natural products, the book provides the know how chemists need to synthesize challenging molecules with numerous applications. It is a must for organic chemists in academia, the pharmaceutical industry and medicine. The contents include: Important Natural Products; Important Pharmaceuticals and Intermediates; Aldol Reactions; Michael Reactions and Conjugate Additions; Cycloaddition Reactions; Rearrangement Reactions; Alkylation of Ketones and Imines; Asymmetric Allylic Alkylation; Asymmetric Cross Coupling and Heck Reactions; Phase Transfer Catalysis; Enzymatic Methods; and, Radical Reactions.

Born in Germany in 1966, Jens Christoffers received his diploma from the University of Marburg, Germany in 1992, before moving to Bonn, Germany, where he completed his doctorate in 1994 on Fischer carbene complexes and Pauson Khand reactions. He became involved with zirconocene catalysis during a post doctorate under Professor R. G. Bergman in Berkeley, USA, and in 1996 started his independent career at the Technical University Berlin, Germany, gaining his lecturing qualification under Professor S. Blechert in 2000. He has been Professor of Organic Chemistry at the University of Stuttgart, Germany, since 2001. Professor Christoffers s current research interests are in the fields of asymmetric catalysis, synthesis of heterocyclic compounds and catalytic oxidation reactions utilizing molecular oxygen. Angelika Baro studied chemistry at the Georg August Universitat Gottingen, Germany, where she received her PhD degree in Clinical Biochemistry in 1987 under the supervision of Professor H. D. Soling. Since 1991 she has been a scientific staff member at the Institute for Organic Chemistry at the University of Stuttgart.

Important Natural Products Important Pharmaceuticals and Intermediates Aldol Reactions Michael Reactions and Conjugate Additions Rearrangement Reactions Cycloaddition Reactions Asymmetric Cross coupling and Mizoroki Heck Reactions Alkylation of Ketones and Imines Asymmetric Allylic Alkylation Phase Transfer Catalysis Radical Reactions Enzymatic Methods

Erscheint lt. Verlag 5.4.2006
Verlagsort Weinheim
Sprache englisch
Gewicht 10 g
Themenwelt Naturwissenschaften Chemie
ISBN-10 3-527-60685-8 / 3527606858
ISBN-13 978-3-527-60685-6 / 9783527606856
Zustand Neuware
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