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Animal Models of Drug Addiction

Mary C. Olmstead (Herausgeber)

Buch | Hardcover
484 Seiten
2010
Humana Press Inc. (Verlag)
978-1-60761-933-8 (ISBN)

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Our understanding of addiction and how it is treated has advanced remarkably over the past decades, and much of the progress is related directly to animal research. This is true for both the behavioural aspects of drug use as well as the biological underpinnings of the disorder. In Animal Models of Drug Addiction, experts in the field provide an up-to-date review of complex behavioural paradigms that model different stages of this disorder and explain how each test is used to effectively replicate the progression of drug addiction. This detailed and practical book begins with the most common laboratory measures of addiction in animals, including intracranial self-stimulation (ICSS), drug self-administration, place conditioning, and sensitization. Later chapters describe how these paradigms are used to model the progression of drug addiction, providing insight into the clinical symptomatology of addiction from acquisition of drug use through compulsive drug taking to withdrawal and relapse. Written for the popular Neuromethods series, the contributions offer both methodological detail and a theoretical perspective, appealing to readers familiar with preclinical research on drug addiction as well as those who are newcomers to the field.

Cutting-edge and authoritative, Animal Models of Drug Addiction will serve as a basis for future vital research that links the bench to the bedside in the crucial treatment of drug addiction.

Intracranial Self-Stimulation.- Stimulant Self-Administration.- Opiate Self-Administration.- Nicotine Self-Administration.- Alcohol Self-Administration.- Place Conditioning.- Sensitization.- Animal Models of Eating Disorders.- Acquisition of Drug Self-Administration.- Escalation of Drug Use.- Environmental Modulation of Drug-Taking.- Craving.- Habit Formation and Compulsion.- Impulsivity.- Binge Drug-Taking.- Withdrawal.- Relapse.

Erscheint lt. Verlag 10.12.2010
Reihe/Serie Neuromethods ; 53
Zusatzinfo XII, 484 p.
Verlagsort Totowa, NJ
Sprache englisch
Maße 178 x 254 mm
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Neurologie
Medizin / Pharmazie Medizinische Fachgebiete Psychiatrie / Psychotherapie
Medizin / Pharmazie Studium
Naturwissenschaften Biologie Humanbiologie
Naturwissenschaften Biologie Zoologie
ISBN-10 1-60761-933-4 / 1607619334
ISBN-13 978-1-60761-933-8 / 9781607619338
Zustand Neuware
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