Fast Oscillations in Cortical Circuits
MIT Press (Verlag)
978-0-262-20118-6 (ISBN)
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The study of cortical oscillations is of great interest to those working in many areas of neuroscience. A fast coherent EEG rhythm called gamma or "40 Hz" has been implicated in cognition, as it may play a role in binding together features of objects. This rhythm may also be important for consciousness, as a number of drugs that induce general anesthesia disrupt the synchronization of the rhythm at clinically relevant concentrations. There is also suggestive evidence implicating dysfunction of gamma rhythms in Alzheimer's disease, and perhaps in other neuropsychiatric disorders.
In Fast Oscillations in Cortical Circuits, the authors use a combination of electrophysiological and computer modeling techniques to analyze how large networks of neurons can produce both epileptic seizures and functionally relevant synchronized oscillations. Specific topics covered include single hippocampal pyramid cells, hippocampal interneurons, synaptic interactions, gamma oscillations in brain slices as well as in vivo, the mechanisms of oscillation-synchronization (both local and long-range), the switch from gamma to beta frequencies and its implications for memory, and the significance of gamma oscillations for brain function.
Terrence J. Sejnowski holds the Francis Crick Chair at the Salk Institute for Biological Studies and is a Distinguished Professor at the University of California, San Diego. He was a member of the advisory committee for the Obama administration's BRAIN initiative and is President of the Neural Information Processing (NIPS) Foundation. He has published twelve books, including (with Patricia Churchland) The Computational Brain (25th Anniversary Edition, MIT Press). Tomaso A. Poggio is Eugene McDermott Professor in the Department of Brain and Cognitive Sciences at MIT, where he is also Director of the Center for Brains, Minds, and Machines and Codirector of the Center for Biological and Computational Learning. He is coeditor of Perceptual Learning (MIT Press).
| Reihe/Serie | Computational Neuroscience Series |
|---|---|
| Verlagsort | Cambridge, Mass. |
| Sprache | englisch |
| Maße | 152 x 229 mm |
| Gewicht | 658 g |
| Themenwelt | Naturwissenschaften ► Biologie ► Humanbiologie |
| Naturwissenschaften ► Biologie ► Zoologie | |
| ISBN-10 | 0-262-20118-6 / 0262201186 |
| ISBN-13 | 978-0-262-20118-6 / 9780262201186 |
| Zustand | Neuware |
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