Chromatin and Gene Regulation

Molecular Mechanisms in Epigenetics

Bryan M. Turner (Autor)

Buch | Softcover

304 Seiten

2001
Wiley-Blackwell (Verlag)
978-0-86542-743-3 (ISBN)

Titel z.Zt. nicht lieferbar
Versandkostenfrei
Auch auf Rechnung

Artikel merken

* Explains the fundamental concept of what makes a cell different from another in simple terms in this exciting and rapidly developing area of modern biology. * Includes a colour plate section. * An up--to--date and essential new textbook which will compliment Whitea s Gene Transcription: Mechanisms and Control.

Written in an informal and accessible style, Chromatin and Gene Regulation enables the reader to understand the science of this rapidly moving field. Chromatin is a fundamental component in the network of controls that regulates gene expression. Many human diseases have been linked to disruption of these control processes by genetic or environmental factors, and unravelling the mechanisms by which they operate is one of the most exciting and rapidly developing areas of modern biology. Chromatin is central both to the rapid changes in gene transcription by which cells respond to changes in their environment and also to the maintenance of gene expression patterns from one cell generation to the next. This book will be an invaluable guide to undergraduate and postgraduate students in the biological sciences and all those with an interest in the medical implications of aberrant gene expression.

Bryan M. Turner is Professor of Experimental Genetics at School of Cancer Sciences, Institute of Biomedical Research, University of Birmingham in Birmingham, UK. He was educated at University College London, where he earned his BSc in Biochemistry and PhD in Human Biochemical Genetics.

Prologue. .

1. Controlling transcription: shared aims and common mechanisms.

.

2. Transcription in eukaryotes: the problems of complexity.

.

3. The nucleosome: chromatin's structural unit.

.

4. Histone tails: modifications and epigenetic information.

.

5. Higher-order chromatin structures and nuclear organisation.

.

6. Transcription in a chromatin environment.

.

7. How the transcription machinery deals with chromatin.

.

8. Chromatin remodelling machines.

.

9. Heterochromatin.

.

10. Long-term silencing of gene expression.

.

11. Cellular memory and imprinting.

.

12. Mechanisms of dosage compensation

Erscheint lt. Verlag	19.12.2001
Verlagsort	Hoboken
Sprache	englisch
Maße	173 x 245 mm
Gewicht	644 g
Themenwelt	Naturwissenschaften ► Biologie ► Allgemeines / Lexika
	Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie
	Naturwissenschaften ► Biologie ► Zellbiologie
ISBN-10	0-86542-743-7 / 0865427437
ISBN-13	978-0-86542-743-3 / 9780865427433
Zustand	Neuware