The Chemistry and Biology of Benz[a]anthracenes

M. S. Newman, B. Tierney, S. Veeraraghavan (Autoren)

Buch | Softcover

244 Seiten

2009
Cambridge University Press (Verlag)
978-0-521-10589-7 (ISBN)

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First published in 1988, this volume surveys the chemical synthesis and biological activity of the benz[a]anthracenes. These compounds occur in smoke and mineral oils and a few have been shown to be potent carcinogens. This volume was the first to review, systematically and in depth, the organic synthesis of these compounds as well as their metablolism, interactions with nucleic acids and protein, mutagenicity and carcinogenicity. Such studies have important implications in determining mechanism and specificity of chemically induced carcinogenesis.

Part I. Chemistry: 1. Synthetic routes from benzenes and naphthalenes; 2. Synthetic routes from anthracenes (A-ring formation); 3. Synthetic routes from anthracenes (D-ring formation); Part II. Biology: 8. Metabolism; 9. DNA, RNA and protein interactions; 10. Mutagenicity; 11. Carciogenicity; References; Index.

Erscheint lt. Verlag	4.6.2009
Reihe/Serie	Cambridge Monographs on Cancer Research
Zusatzinfo	Worked examples or Exercises
Verlagsort	Cambridge
Sprache	englisch
Maße	152 x 229 mm
Gewicht	360 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie
Themenwelt	Studium ► 2. Studienabschnitt (Klinik) ► Pathologie
ISBN-10	0-521-10589-7 / 0521105897
ISBN-13	978-0-521-10589-7 / 9780521105897
Zustand	Neuware