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Predictive Diagnostics & Personalized Treatment -

Predictive Diagnostics & Personalized Treatment

Dream or Reality

Olga Golubnitschaja (Herausgeber)

Buch | Hardcover
621 Seiten
2009
Nova Science Publishers Inc (Verlag)
978-1-60692-737-3 (ISBN)
CHF 589,95 inkl. MwSt
Conventional medicine and new branches of biomedicine are challenging many issue-related questions: How reliable are biomarkers for any given pathology? How to distinguish between the highly predictive power of innovation and quackery in diagnostics? This book addresses these issues and provides some clues for plausible solutions.
Predictive, preventive and personalised medicine offers great promise for the future practice of medicine. Essential components of this approach include well-organised population screening protocols utilising novel diagnostic biomarkers of disease states, targeted prevention of common human pathologies, optimal treatment planning and personalised medicine thereby resulting in substantial improvement of the quality of life. This approach also offers the advantage of delivering care at potentially reduced costs to the population at large thereby addressing social and ethical issues related to access to and affordability of health care. Consequently, conventional medicine and new branches of biomedicine are currently challenging many issue-related questions: Should molecular diagnostic approaches be considered complementary or substitutive measures to conventional approaches? How reliable are biomarkers for any given pathology? How to distinguish between the highly predictive power of innovation and quackery in diagnostics? How to overcome currently well-recognisable (inter)national barriers in knowledge transfer? How to correctly educate the new generation of experts in bio- and predictive medicine? The book addresses these highly relevant issues and provides some clues for plausible solutions. The information presented in this book emphasises the necessity of individualised patient treatment and provides compelling reasons as to why "across-the-board" treatment is not warranted. Application of nutritional proteomics results in individualised optimal diet and may potentially restrict the epidemic scale of type 2 Diabetes mellitus. A broad distribution and a routine clinical utilisation of these advanced technological approaches could enable a significant portion of the population to reach the 100-year age limit yet remaining vibrant in excellent physical and mental health and as actively contributing members of society. The examples given in the book are based on well-recognised expertise, scientific publications and international patents. A panel of leading world experts and authorities of the international issue-related associations have contributed to the book by addressing relevant issues and topics such as model-based patient-care and individualised therapy-planning, reproductive medicine and postnatal diagnostics, early/predictive diagnosis and optimised treatment of cancer as well as the most frequent neurodegenerative disorders.

Predictive Medicine as the new philosophy in health care; The role and predictive power of cell cycle checkpoints in aging, cardiovascular, cancer, and neurodegenerative diseases; Circulating Nucleic Acids in Plasma and Serum: Roles in Diagnosis and Prognosis; Pharmacogenetics and prediction of drug response; Prediction of Degeneration of Native and Bioprosthetic Aortic Valves; Gene therapy and individualized medicine; Model-based patient care with a therapy imaging and model management system; Diabetes Care: Risk factors, Prediction, Prevention, Therapy; Introduction; New tendencies in the epidemiology of Diabetes mellitus; Diabetic Complications: Pathogenic Mechanisms and Prognostic Indicators; Schaffer); Potential predictive biomarkers for the dysfunction of ss-cells in type 2 diabetes; Advanced technologies for prediction of secondary complications in Diabetes mellitus; Prevalence, targeted treatment and prevention of eye disorders in Diabetes; Diabetes mellitus as a risk factor for cancer: Is predictive diagnosis possible?; Multiple drug resistance associated with function of ABC-transporters in Diabetes mellitus: Molecular mechanism and clinical relevance; Advanced drug delivery systems in Diabetes treatment; Prediction and targeted treatment of neurodegenerative disorders; Prediction and targeted prevention of Parkinson's and Alzheimer's diseases; Multiple sclerosis related biomarkers; What are the biomarkers for Glaucoma?; Prediction and targeted treatment of cancer; Integrated diagnostics and personalized therapeutics in oncology; How realistic are non-invasive approaches in breast cancer prediction?; Are side-effects of irradiation predictable for treatment of breast cancer patients?; Prediction of pro-invasive potential in treated malignant gliomas: Engineering of clinical treatment; Biomarker discovery in glioma by combined approach of laser microdissection and advanced mass spectrometry; Predictive Diagnosis in Reproductive Medicine and Pediatrics; Proteomics-based prediction in prenatal diagnosis and reproductive medicine; Birth asphyxia as the most frequent perinatal complication; Potential targets for early diagnosis and neuroprotection in asphyxiated newborns; Informatics, Economics, Knowledge Transfer and Patents in Predictive Medicine; Information systems as an essential component of prediction in the laboratory diagnostics; Economic aspects and the role of insurance in predictive diagnostics; Knowledge transfer and patenting strategy in predictive medicine; Index.

Erscheint lt. Verlag 10.8.2009
Zusatzinfo Illustrations
Verlagsort New York
Sprache englisch
Maße 260 x 180 mm
Gewicht 1540 g
Themenwelt Studium 2. Studienabschnitt (Klinik) Anamnese / Körperliche Untersuchung
ISBN-10 1-60692-737-X / 160692737X
ISBN-13 978-1-60692-737-3 / 9781606927373
Zustand Neuware
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