Insulin Resistance
Nova Science Publishers Inc (Verlag)
978-1-60692-332-0 (ISBN)
Insulin resistance is defined as an impaired biological response to either exogenous or endogenous insulin. It is an increasingly prevalent disorder in the developed countries and is known as a high risk factor for both cardiovascular diseases and malignancies. This book describes the endocrine disorders that are associated with changes in insulin sensitivity, often resulting in clinical consequences such as impaired glucose tolerance or secondary diabetes mellitus. The main components of a pathological condition known as metabolic syndrome (MS) or syndrome X is also described, including insulin resistance, type II diabetes, hypertension, central obesity, dyslipidemia, and nephropathy. The treatment of type II diabetes is examined, including the adjustments to changes in insulin resistance and secretion and to variations in basal and prandial glucose along the diabetes continuum. The prevalence of insulin resistance among children and adolescents is also looked at, including insulin resistance in childhood cancer survivors. In addition, the association between insulin resistance and oral cancer risk (i.e. smoking) is addressed, as well as the roles of insulin resistance and sympathetic nerve activity in obesity, hypertension, Turner syndrome and liver disease. The association between non-alcoholic fatty liver disease (NAFLD) and insulin resistance, and the pathogenetic and therapeutic implications are also addressed.
Preface; Insulin Resistance in Endocrine Disorders; Insulin Resistance and the Metabolic Syndrome; Fetuin-A, a Novel Regulator of Insulin Action: Role in Insulin Resistance; Insulin Resistance and Endothelial Dysfunction: An Unhappy Union; Treatment of Type 2 Diabetes: Adjustments to Changes in Insulin Resistance and Secretion and to Variations in Basal and Prandial Glucose along the Diabetes Continuum; Is the Metabolic Syndrome Associated per se with Chronic Inflammation?; The Metabolic Syndrome as a Concept of Adipose Tissue Disease; Surveillance of Insulin Resistance in Children and Adolescents; The Causes of the Metabolic Syndrome - An Asian Perspective; Insulin Resistance in Childhood Cancer Survivors: A Link between Metabolic Syndrome Features; Insulin Resistance and Oral Cancer Risk; The Roles of Insulin Resistance and Sympathetic Nerve Activity in Obesity and Hypertension - which comes first in Hypertension and Obesity?; Insulin Resistance: New Research (Insulin Resistance and Liver Disease); Turner Syndrome and Insulin Resistance: Reviewing this Complex Association; Association between Non-Alcoholic Fatty Liver Disease (NAFLD) and Insulin Resistance: Pathogenetic and Therapeutic Implications; Association of Plasma Homocysteine to Insulin Resistance and Metabolic Syndrome Components in Healthy Omnivores and Vegetarians; Effect of Insulin Resistance on Coronary In-Stent Restenosis; MRI Measurement of Visceral Fat & Epicardial Adipose Tissue; Expression of Inflammatory Molecules in an Experimental Vascular Remodeling Model; Methods of Insulin Resistance Assessment; Insulin-Sensitising Effects of Telmisartan via Peroxisome Proliferator-Activated Receptor-y Activation; Index.
| Erscheint lt. Verlag | 17.12.2009 |
|---|---|
| Zusatzinfo | Illustrations |
| Verlagsort | New York |
| Sprache | englisch |
| Maße | 260 x 180 mm |
| Gewicht | 1060 g |
| Themenwelt | Medizinische Fachgebiete ► Innere Medizin ► Endokrinologie |
| ISBN-10 | 1-60692-332-3 / 1606923323 |
| ISBN-13 | 978-1-60692-332-0 / 9781606923320 |
| Zustand | Neuware |
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