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Opioids In Cancer Pain -

Opioids In Cancer Pain

Buch | Hardcover
504 Seiten
2009 | 2nd edition
Oxford University Press (Verlag)
978-0-19-923664-0 (ISBN)
CHF 127,40 inkl. MwSt
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Opioids can be effective in relieving pain in more than 90% of cancer patients. However, often irrational fears from both patients and clinicians persist about the potential for addiction, meaning treatable pain continues to be tolerated. This book offers clear guidelines on the use of opioids when managing cancer pain.
Opioids have become invaluable in modern medicine but it is essential that they are prescribed with an understanding of the complex pharmacology behind their effectiveness; without this, they will frequently fail to achieve their enormous potential of pain relief, minimal side effects, and improved function. In addition, opioids come with problems, including side effects such as constipation, respiratory depression, and sedation, as well as the potential for substance abuse. Clinicians handling the complex pain problems of cancer patients must incorporate the insight of basic scientists and pharmacologists, and this new edition of this comprehensive text brings together a wealth of experience from those involved in all aspects of opioids, with a view to improving both clinician understanding and patient care. The text includes comprehensive coverage of the principles of opioid pharmacodynamics, pharmacokinetics, and pharmacogenetics. A chapter is dedicated to each of the main opioids, with topics such as structure, routes of administration, toxicity, drug interactions, and effects on organ function included within each one.
The book concludes with several chapters dedicated to discussion of the major issues relevant to opioid use, including substance abuse, dosing strategies for acute and chronic pain, patient controlled analgesia, equianalgesia, spinal opioids, pain that doesn't respond to opioids, and the terminal phase. This text is the most complete and extensive work available on the use of opioids for cancer pain, and is an important reference for those clinicians treating individuals with cancer.

Columba Quigley previously held the post of Deputy Coordinating Editor of the Cochrane Collaboration Pain Palliative and Supportive Care Group. She has lectured and published in a range of areas, including opioid switching, alternative opioids, inter-individual variability in opioid responsiveness and the genetics of opioid response.

1. Opioid receptors and opioid pharmacodynamics ; 2. Opioid pharmacokinetics ; 3. Liver disease and exogenous opioid pharmacokinetics ; 4. Opioids in renal failure ; 5. Codeine ; 6. Hydrocodone ; 7. Tramadol ; 8. Dextropoxyphene ; 9. Morphine ; 10. Oxycodone ; 11. The lipophilic opioids - fentanyl, alfentanil, sufentanil and remifentanil ; 12. Buprenorphine ; 13. Methadone ; 14. Hydromorphone ; 15. Levorphanol ; 16. Diamorphine ; 17. Oxymorphone ; 18. Choice of opioids and the WHO ladder ; 19. Pharmacogenetics and opioids ; 20. Opioid rotation ; 21. Equianalgesia ; 22. Dosing strategies for acute pain ; 23. Opioid dosing strategies for chronic pain and the management of opioid side effects ; 24. Patient controlled analgesia ; 25. Spinal opioids in cancer pain ; 26. Opioid poorly responsive pain, physical dependence, tolerance and opioid-induced hyperalgesia ; 27. Opioids in special populations: developing countries ; 28. Opioids in special populations: pediatric population ; 29. Opioids in the terminal phase ; 30. Cancer pain and substance abuse

Zusatzinfo 33 black-and-white line drawings
Verlagsort Oxford
Sprache englisch
Gewicht 1014 g
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Onkologie
Medizin / Pharmazie Medizinische Fachgebiete Palliativmedizin
Medizin / Pharmazie Medizinische Fachgebiete Pharmakologie / Pharmakotherapie
Medizin / Pharmazie Medizinische Fachgebiete Schmerztherapie
Medizin / Pharmazie Pflege Palliativpflege / Sterbebegleitung
ISBN-10 0-19-923664-X / 019923664X
ISBN-13 978-0-19-923664-0 / 9780199236640
Zustand Neuware
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