The Prevention of Cancer

Pointers from Epidemiology

Richard Doll (Autor)

Buch | Softcover

144 Seiten

2008
AldineTransaction (Verlag)
978-0-202-36220-5 (ISBN)

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Epidemiological studies show that cancer incidence is far more dependent on the conditions of life than previously supposed. Classically, cancers occurred with heavy exposure to a specific occupational hazard, or were associated with habits. In some instances, research shows, the incidence of cancer falls when the method of work or the associated habit is changed. In short, variation in incidence is now known to be the rule rather than the exception in cancer. No cancer that occurs with even moderate frequency, occurs everywhere and always to the same extent. Sometimes it is even epidemic, similar in scale to an epidemic of infectious disease, but modified by the fact that the induction period may be as much as thirty years.

Prevention of cancer is now coming to be regarded as a practicable alternative to its cure. We remain almost totally ignorant of how cancer is produced at the cellular level and, until we know this, our methods of prevention are liable to be cumbersome and inefficient. Ethical considerations and the time scale of the disease make it impossible to obtain experimental evidence in man and what action to take has been determined from observing nature's experiments and by analogy from experiments in animals.

The evidence from epidemiological studies is of particular interest. Such studies suggest relationships that would never be thought of in the ordinary course of laboratory work and results that are directly relevant to the problems of human disease. The large numbers at risk and the intensity of the medical care to which people with cancer are subjected, make it possible to recognize relatively small improvements. Such practical decisions, based on information thus obtained, have largely eliminated the risk of cancer due to occupational hazards in several industries.

Richard Doll (1912-2005) was a British psychologist and one of the most prominent epidemiologists of the twentieth century. Throughout out his research he was able to link smoking with health problems and was the first individual to link smoking with lung cancer and increased risk of heart disease. He also studies the relationship between asbestos and lung cancer and radiation and leukemia. He is the author of many books including The Causes of Cancer: Quantitative Estimates of Avoidable Risks of Cancer in the United States Today and Tobacco and Health.

1: Introduction; 2: The Nature of Epidemiological Evidence; 3: The Geographical and Temporal Distribution; 4: Aetiological Factors; 5: The Dose-Response Relationship; 6: Variation in Individual Susceptibility; 7: The Cancer Process; 8: Practical Steps to Prevention; Epilogue

Erscheint lt. Verlag	15.7.2008
Verlagsort	Somerset
Sprache	englisch
Maße	152 x 229 mm
Gewicht	249 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie
Themenwelt	Studium ► Querschnittsbereiche ► Epidemiologie / Med. Biometrie
ISBN-10	0-202-36220-5 / 0202362205
ISBN-13	978-0-202-36220-5 / 9780202362205
Zustand	Neuware