Stem Cell Research Developments

Buch | Hardcover

314 Seiten

2007
Nova Science Publishers Inc (Verlag)
978-1-60021-601-5 (ISBN)

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Stem cells are primal cells common to all multi-cellular organisms that retain the ability to renew themselves through cell division and can differentiate into a range of specialised cell types. This book presents research in this field.

Stem cells are primal cells common to all multi-cellular organisms that retain the ability to renew themselves through cell division and can differentiate into a wide range of specialised cell types. The two broad categories of mammalian stem cells exist: embryonic stem cells, derived from blastocysts, and adult stem cells, which are found in adult tissues. In a developing embryo, stem cells are able to differentiate into all of the specialised embryonic tissues. In adult organisms, stem cells and progenitor cells act as a repair system for the body, replenishing specialised cells. As stem cells can be readily grown and transformed into specialised tissues such as muscles or nerves through cell culture, their use in medical therapies has been proposed. In particular, embryonic cell lines, autologous embryonic stem cells generated therapeutic cloning, and highly plastic adult stem cells from the umbilical cord blood or bone marrow are touted as promising candidates. Among the many applications of stem cell research are nervous system diseases, diabetes, heart disease, auto-immune diseases as well as Parkinson's disease, end-stage kidney disease, liver failure, cancer, spinal cord injury, multiple sclerosis, Parkinson's disease, and Alzheimer's disease. Stem cells are self-renewing, unspecialised cells that can give rise to multiple types all of specialised cells of the body. Stem cell research also involves complex ethical and legal considerations since they involve adult, foetal tissue and embryonic sources. This book presents important research in this field.

Preface; Stem Cells, Progenitor Cells and Vascular Diseases; GATA Transcription Factors and T Cell Development from Hematopoietic Stem Cells; Protein Tyrosine Phosphatase Shp-2 in Cytokine Signallings and Stem Cell Regulations; Stem Cells for Neural Tissue Engineering; Fibrocytes, Mesenchymal Stem Cells and Monocytes: Who is who in Circulating Stem Cells?; Neural Stem Cell Niche-dependency: A Theoretical Model of spatially restricted responses to the activation of multiple Receptors; Potential Application of Human Umbilical Cord Mesenchymal Stem Cells in Wharton's Jelly for the treatment of Parkinsonism; Human Oogenesis and Follicular Renewal from Ovarian Somatic Stem Cells; Gastric Stem Cells; Index.

Erscheint lt. Verlag	15.8.2007
Zusatzinfo	Illustrations
Verlagsort	New York
Sprache	englisch
Maße	260 x 180 mm
Gewicht	858 g
Themenwelt	Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik
ISBN-10	1-60021-601-3 / 1600216013
ISBN-13	978-1-60021-601-5 / 9781600216015
Zustand	Neuware