Intestinal Inflammation and Colorectal Cancer
Springer-Verlag New York Inc.
978-1-4020-6825-6 (ISBN)
This book is the proceedings of the Falk Symposium 158, on Intestinal Inflammation and Colorectal Cancer, held in March 2007. It covers the current understanding of inflammation-driven colon carcinogenesis, highlights the most relevant mechanisms and discusses measures to interfere with this process. This is a true translational topic which will attract both basic scientists and clinicians, specifically those who can make a difference in preventing this type of cancer.
Epidemiology of the villain.- Colorectal cancer in patients with inflammatory bowel disease: influence of nutritional habits and environmental clues.- Inflammatory bowel disease high-risk groups.- Not all colorectal cancers are the same.- Getting familiar with familial colon cancer.- The adenomatous polyposis coli tumour-suppressor protein in normal gut tissue maintenance and cancer.- Mismatch repair competency predicts 5-fluorouracil effectiveness on patient survival.- Inflammatory bowel disease-related cancer — just the same as sporadic? — Pro.- Differences between sporadic and colitis-associated colorectal cancer.- Screening and surveillance.- Endoscopic guidelines for hereditary non-polyposis colorectal cancer, familial adenomatous polyposis, inflammatory bowel disease and sporadic colorectal cancer.- Which new techniques will replace classical surveillance?.- How to deal with dysplasia and adenomatous polyps in inflammatory bowel disease.- Taking dysplasia to the molecular level.- Inflammation driven carcinogenesis: the players.- Cancer originating from bone marrow stem cells: can we extrapolate from gastritis to colitis?.- Translating laboratory findings into clinics: of mice and man.- How can we prevent?.- Inner and outer environment.- Can we prevent inflammatory bowel disease-related colorectal cancer with 5-aminosalicylic acid, azathioprine, or 6-mercaptopurine? The clinical evidence.- How can we prevent colorectal cancer with ursodeoxycholic acid?.- Molecular actions of 5-ASA — the magic bullet.- 5-Aminosalicylic acid and replication fidelity.- New mechanisms of action of 5-aminosalicylic acid: PPAR?: how it decreases inflammation and cancer.- Mesalazine and the prevention of colorectal cancer in inflammatory bowel disease.- Mesalazine and cell cycleprogression.- Chemopreventive role of mesalazine in inflammatory bowel disease-associated colorectal cancer: the role of DNA methylation.- Molecular actions of 5-aminosalicylic acid: the magic bullet on epidermal growth factor receptor signalling.- State-of-the-Art Lecture.- State-of-the-Art Lecture: Infection, inflammation and cancer — the future.- Progression of cancer through inflammatory mechanisms.- An integrating concept of malignant progression in colorectal cancer.- The balance between survival and apoptosis.- The tumour microenvironment regulates components of the fucose biosynthesis pathways in colorectal cancer cells.
| Reihe/Serie | Falk Symposium ; 158 |
|---|---|
| Zusatzinfo | XV, 320 p. |
| Verlagsort | New York, NY |
| Sprache | englisch |
| Maße | 155 x 235 mm |
| Themenwelt | Medizinische Fachgebiete ► Chirurgie ► Viszeralchirurgie |
| Medizinische Fachgebiete ► Innere Medizin ► Gastroenterologie | |
| Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie | |
| ISBN-10 | 1-4020-6825-5 / 1402068255 |
| ISBN-13 | 978-1-4020-6825-6 / 9781402068256 |
| Zustand | Neuware |
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