Cytogenetics, FISH and Molecular Testing in Hematologic Malignancies

Buch | Hardcover

332 Seiten

2008
CRC Press (Verlag)
978-0-415-42009-9 (ISBN)

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Cytogenetics, fluorescence in situ hybridization (FISH) and molecular tests, especially polymerase chain reaction (PCR), play an important role in the management of patients with hematologic malignancies by helping to establish the diagnosis, as well as predict prognosis, response to treatment and disease progression. Chromosomal and molecular abnormalities provide the most reliable criteria for classification of hematopoietic tumors and often comprise the basis for targeted therapy.

Cytogenetics, FISH and Molecular Testing in Hematologic Malignancies, provides a review of chromosomal and molecular changes in hematologic malignancies and correlates the karyotypic and genetic abnormalities with morphology, immunophenotype and clinical data. With over 180 figures and diagnostic algorithms, this text is essential reading for all pathologists, hematopathologists, hematologic oncologists, cytogenetists, cytogenetic technologists and cell biologists.

Director of Hematopathology/Oncology Services (New York), Genzyme Genetics, USA

Chapter I. Introduction. Chapter II. Applications of cytogenetics, FISH and PCR in the diagnosis, prognosis and disease monitoring. Chapter III. Hematological malignancies: Correlation between morphology, phenotype and chromosomal/genetic markers.

Erscheint lt. Verlag	1.8.2008
Zusatzinfo	24 Tables, black and white; 56 Line drawings, color; 4 Line drawings, black and white; 186 Halftones, color; 45 Halftones, black and white
Verlagsort	London
Sprache	englisch
Maße	189 x 246 mm
Gewicht	1088 g
Themenwelt	Medizin / Pharmazie ► Allgemeines / Lexika
ISBN-10	0-415-42009-1 / 0415420091
ISBN-13	978-0-415-42009-9 / 9780415420099
Zustand	Neuware