Ischemia-Reperfusion Pathways in Alzheimer's Disease
Nova Science Publishers Inc (Verlag)
978-1-60021-744-9 (ISBN)
This book is a study of the neurobiology of Alzheimer's disease. The authors critically review the established and accepted culprit in alzheimer's disease, the amyloid, the main molecular factor of neurodegeneration in this disease. This book provides a synopsis of current information about ischemic cellular and molecular mediators involved in Alzheimer's neuropathology as well as interactions between these mediators that influence pathology. Current knowledge on the relation between ischemia-reperfusion factors and Alzhemier's-type demential will be reviewed and the linking of B-amyloid deposition to neuronal damage and clinical disease.
Preface; Cerebrovascular damage: a cause for Alzheimers disease?; Relationships between brain ischemia and Alzheimers disease -- Insights derived from pre-clinical animal models; Hyperthermia following ischemia-reperfusion as a valuable tool for pre-clinical development of therapeutic strategies relevant to human dementias; Alzheimers disease pathological factors in ischemic aged brain; Transient occlusion of the middle cerebral artery in rats leads to permanent amyloid deposits in the thalamus; Thalamic calcification and amyloid deposition following focal cerebral ischemia in rats; Ischemia-Reperfusion Promotes Tau and Beta-Amyloid Pathology and a Progressive Cognitive; Is the Ischemic blood-brain barrier a Trojan horse in Alzheimer's Disease brain?; Treatment of Alzheimer's Disease: New Insights from Treatment of Stroke at Delayed Time Points; Index.
| Zusatzinfo | Illustrations |
|---|---|
| Verlagsort | New York |
| Sprache | englisch |
| Maße | 260 x 180 mm |
| Gewicht | 654 g |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Geriatrie |
| Medizinische Fachgebiete ► Innere Medizin ► Kardiologie / Angiologie | |
| ISBN-10 | 1-60021-744-3 / 1600217443 |
| ISBN-13 | 978-1-60021-744-9 / 9781600217449 |
| Zustand | Neuware |
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