Histopathology of Preclinical Toxicity Studies
Interpretation and Relevance in Drug Safety Evaluation
Seiten
2007
|
3rd edition
Elsevier Science Ltd (Verlag)
978-0-444-52771-4 (ISBN)
Elsevier Science Ltd (Verlag)
978-0-444-52771-4 (ISBN)
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Covers various aspects of drug-induced pathology that may be encountered within preclinical toxicity studies. This work relates to the preclinical safety assessment of new medicines. It also covers drug induced pathology in preclinical (animal) studies and their relevance for patients or volunteers in clinical studies.
This work covers effectively all aspects of drug-induced pathology that may be encountered within preclinical toxicity studies. It fills a gap in the pathology literature relating to the preclinical safety assessment of new medicines. It systematically describes, in one volume, both spontaneous and drug induced pathology on an organ by organ basis. Information relevant to understanding the nature of pathological changes in pre-clinical studies and assessment of their relevance to the clinical investigation of new drugs is also covered. Numerous colour photographs are included that highlight and embellish the histopathological features that are described. It also contains many pertinent references to both human and animal pathology forming an essential basis for the assessment of drug-induced pathology.
This work covers effectively all aspects of drug-induced pathology that may be encountered within preclinical toxicity studies. It fills a gap in the pathology literature relating to the preclinical safety assessment of new medicines. It systematically describes, in one volume, both spontaneous and drug induced pathology on an organ by organ basis. Information relevant to understanding the nature of pathological changes in pre-clinical studies and assessment of their relevance to the clinical investigation of new drugs is also covered. Numerous colour photographs are included that highlight and embellish the histopathological features that are described. It also contains many pertinent references to both human and animal pathology forming an essential basis for the assessment of drug-induced pathology.
MBChB, FRCPath, Consulting Pathologist and Honorary Senior Lecturer, Department of Cancer Studies and Molecular Medicine, University of Leicester, UK
Chapter 1: Introduction
Chapter 2: Integumentary System
Chapter 3: Mammary Gland
Chapter 4: Haemopoietic and Lymphatic Systems
Chapter 5: Musculoskeletal System
Chapter 6: Respiratory Tract
Chapter 7: Cardiovascular System
Chapter 8: Digestive System
Chapter 9: Liver and Pancreas
Chapter 10: Urinary Tract
Chapter 11: Male Genital Tract
Chapter 12: Female Genital Tract
Chapter 13: Endocrine Glands
Chapter 14: Nervous System and Special Sense Organs
Subject Index
| Erscheint lt. Verlag | 23.2.2007 |
|---|---|
| Verlagsort | Oxford |
| Sprache | englisch |
| Maße | 165 x 240 mm |
| Gewicht | 10 g |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Laboratoriumsmedizin |
| Studium ► 2. Studienabschnitt (Klinik) ► Pathologie | |
| Studium ► 2. Studienabschnitt (Klinik) ► Pharmakologie / Toxikologie | |
| ISBN-10 | 0-444-52771-0 / 0444527710 |
| ISBN-13 | 978-0-444-52771-4 / 9780444527714 |
| Zustand | Neuware |
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