Varicella-Zoster Virus
Cambridge University Press (Verlag)
978-0-521-66024-2 (ISBN)
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Published in association with the VZV Research Foundation, this is a comprehensive account of the biology and clinical features of the varicella-zoster virus. The successful development of a vaccine reflects intense research interest in this virus over recent years, and this book surveys current knowledge of the molecular biology, pathogenesis and clinical features of VZV as the causative agent of chickenpox and zoster (shingles). Topics covered include viral replication, latency, immune mechanisms, epidemiology and disease manifestations, and complications of varicella and zoster. There is detailed information on live attenuated varicella vaccine, treatment strategies and the management of postherpetic pain in zoster patients. As the most authoritative review and guide to the virus and its diseases, this book will appeal to a wide range of clinicians and investigators, including pediatricians, geriatricians, neurologists, dermatologists and infectious disease specialists, as well as virologists interested in the herpes viruses.
Preface Anne Gershon; Introduction and dedication Ann Arvin and Anne Gershon; Part I. History: 1. Historical perspective Thomas Weller; Part II. Molecular Biology and Pathogenesis: 2. Molecular evolution of alphaherpes viruses Andrew Davison; 3. DNA replication John Hay and William Ruyechan; 4. Viral proteins Jeffrey Cohen and Paul Kinchington; 5. Pathogenesis of primary infection Charles Grose; 6. Pathogenesis of latency and reactivation Stephen Straus and Saul Silverstein; 7. Host response to primary infection Ann Arvin and Allison Abendroth; 8. Host response during latency and reactivation Anthony Hayward; 9. Animal models of VZV infection Catherine Sadzot-Delvaux and Bernard Rentier; Part III. Epidemiology and Clinical Manifestations: 10. Epidemiology Jane Seward; 11. Disease manifestations Phillip LaRussa; 12. Clinical aspects of recurrent infection: herpes zoster Kenneth Schmader; 13. Disease manifestations Michael Oxman; 14. Ophthalmic zoster Deborah Pavan Langston; 15. Postherpetic neuralgia and other neurologic complications Donald Gilden; 16. Varicella and herpes zoster in pregnancy and the newborn Gisela Enders and Elizabeth Miller; Part IV. Laboratory Diagnosis: 17. Laboratory diagnosis of VZV infection Baghar Forghani; Part V. Treatment and Prevention: 18. Management of postherpetic pain Kathryn Elliott; 19. Therapeutic immunization against herpes zoster Myron Levin; 20. Passive immunization against VZV infection Phillip Brunell; 21. Development of the Oka vaccine Michiaki Takahashi and Stanley Plotkin; 22. Primary immunization against varicella Anne Gershon and Paula Annunziato; 23. Epidemiologic implications/surveillance David Weber and Lisa Saiman; 24. Treatment of primary infection: varicella-intact and immunocompromised hosts Richard Whitley; 25. Treatment of recurrent infection: herpes zoster-intact and immunocompromised hosts Martin Wood and Martin Dedicoat; Index.
| Erscheint lt. Verlag | 23.11.2000 |
|---|---|
| Zusatzinfo | 38 Tables, unspecified; 12 Plates, color; 21 Halftones, unspecified; 1 Line drawings, unspecified |
| Verlagsort | Cambridge |
| Sprache | englisch |
| Maße | 185 x 253 mm |
| Gewicht | 1541 g |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Mikrobiologie / Infektologie / Reisemedizin |
| ISBN-10 | 0-521-66024-6 / 0521660246 |
| ISBN-13 | 978-0-521-66024-2 / 9780521660242 |
| Zustand | Neuware |
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