Exploring the Role of Antiviral Drugs in the Eradication of Polio

Workshop Report

Committee on Development of a Polio Antiviral and Its Potential Role in Global Poliomyelitis Eradication, Board on Life Sciences, Division on Earth and Life Studies, National Research Council, National Academy of Sciences (Autoren)

Buch | Softcover

82 Seiten

2006
National Academies Press (Verlag)
978-0-309-10161-5 (ISBN)

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Exploring the Role of Antiviral Drugs in the Eradication of Polio: Workshop Report, is a report of a workshop in which experts evaluated whether an antiviral drug against poliovirus would be helpful in the final stages of the global polio eradication campaign. The World Health Organization currently plans to stop using oral polio vaccine three years after the detection of the last case of transmission of wild polio virus. This is because the vaccine contains live, weakened polio viruses that can spread and revert to virulence in populations that have not been immunized. Under this plan, an antiviral drug could be useful to control any polio outbreaks caused by a vaccine-derived virus that might occur after vaccination ends and the number of unimmunized people in the world steadily increases. The report recommends that planning and development of such drugs should be initiated now. It identifies several promising targets for drug development and outlines the steps needed for planning for clinical trials and regulatory approval.

Committee on Development of a Polio Antiviral and Its Potential Role in Global Poliomyelitis Eradication, National Research Council

1 Front Matter; 2 Summary; 3 1 An Overview of the Polio Eradication Challenge; 4 2 Public Health Considerations; 5 3 Potential Biological Targets for Polio Antiviral Drugs; 6 4 Development of Antiviral Drugs for Polio Virus; 7 5 Implementation and Recommendations; 8 References; 9 Appendix A: Statement of Task; 10 Appendix B: Committee Biographical Sketches; 11 Appendix C: Workshop Agenda and Participant List

Erscheint lt. Verlag	4.6.2006
Verlagsort	Washington
Sprache	englisch
Maße	152 x 229 mm
Themenwelt	Studium ► Querschnittsbereiche ► Epidemiologie / Med. Biometrie
ISBN-10	0-309-10161-1 / 0309101611
ISBN-13	978-0-309-10161-5 / 9780309101615
Zustand	Neuware