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A Pharmacology Primer - Terry P. Kenakin

A Pharmacology Primer

Theory, Applications, and Methods
Buch | Softcover
320 Seiten
2006 | 2nd edition
Academic Press Inc (Verlag)
978-0-12-370599-0 (ISBN)
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Dealing with the basics of pharmacology, this work features historical facts in pharmacology. It contains a section on therapeutics to help readers identify with diseases and drug treatments. It also features over 30 figures and tables and a coverage of pharmacokinetics and drug disposition.
The Second Edition will continue this tradition of better preparing researchers in the basics of pharmacology. In addition, new human interest material including historical facts in pharmacology will be added. A new section on therapeutics will help readers identify with diseases and drug treatments.

Dr. Terry Kenakin is Professor of Pharmacology at the University of North Carolina School of Medicine. Prior to this, he spent 7 years in drug discovery at Burroughs-Wellcome. He then moved to GlaxoSmithKline for 25 years. Dr. Kenakin has written 11 books on Pharmacology, is the Editor in Chief of the Journal of Receptors and Signal Transduction, is on numerous Editorial Boards. He is the Editor-in-Chief of Comprehensive Pharmacology (Elsevier, 2022). He is the recipient of the 2008 Poulsson Medal for Pharmacology awarded by the Norwegian Society of Pharmacology for achievements in basic and clinical pharmacology and toxicology. He has also been awarded the 2011 Ariens Award from the Dutch Pharmacological Society and the 2014 Gaddum Memorial Award from the British Pharmacological Society, and the 2020 Goodman and Gilman Award in Receptor Pharmacology from ASPET.

Chapter 1: What Is Pharmacology?

Chapter 2: How Different Tissues Process Drug Response

Chapter 3: Drug-Receptor Theory

Chapter 4: Pharmacological Assay Formats: Binding

Chapter 5: Agonists: The Measurement of Affinity and Efficacy in Functional Assays

Chapter 6: Orthosteric Drug Antagonism

Chapter 7: Allosteric Drug Antagonism

Chapter 8: The Process of Drug Discovery

Chapter 9: Target- and System-based Strategies for Drug Discovery

Chapter 10: “Hit” to Drug: Lead Optimization

Chapter 11: Statistics and Experimental Design

Chapter 12: Selected Pharmacological Methods

Glossary of Pharmacological Terms

Appendices

Index

Erscheint lt. Verlag 27.10.2006
Verlagsort San Diego
Sprache englisch
Maße 216 x 279 mm
Gewicht 962 g
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Pharmakologie / Pharmakotherapie
Medizin / Pharmazie Pharmazie
ISBN-10 0-12-370599-1 / 0123705991
ISBN-13 978-0-12-370599-0 / 9780123705990
Zustand Neuware
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