Cell Signaling

Interplay, Mechanisms, and Therapeutic Implications

Buch | Hardcover

400 Seiten

2025
CRC Press (Verlag)
978-1-032-70744-0 (ISBN)

Noch nicht erschienen (ca. April 2025)
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This book provides a comprehensive understanding of cell signaling, molecular interactions, and its implications for human health and diseases. It introduces fundamental principles underlying cell communication through signaling molecules and their diverse transmission and reception mechanisms, highlighting their role in intercellular communication through voltage and ion gated channels, immunological and neuron synapses and rhinovirus-receptor interaction involved in the pathogenesis and disease development. Towards the end, the book highlights the profound implications of altered cell signaling pathways in the inflammation and immune response followed by progression of various disorders, including cancer, endocrine disorders, and neurological illnesses. It explores diagnostic and therapeutic implications of cell signaling in targeted therapies, highlighting advanced techniques for detecting signaling molecules and innovative therapeutic approaches to inspire new developments in precision medicine. It serves as an important resource for academics, students, and professionals in the fields of cell biology and biomedical sciences.

Key Features:

1) Provides in-depth understanding of cell signaling, exploring its complexities and impact on human health and disease.

2) Introduces fundamental principles of cell communication, emphasizing the different signaling molecules and their various transmission pathways.

3) Focuses on complex structures and functions of receptors, highlighting their essential role in intercellular communication and regulating cellular behavior.

4) Examines the molecular aspects of cell surface adhesion receptors, elucidating protein-protein interactions, signaling cascades, and enzyme-substrate interactions.

5) Discusses the impact of cell signaling on inflammation, cancer, endocrine, and neurological disorders.

Dr Adeeb Shehzad is currently Associate Professor at Biodiversity Unit, Research Center, Dhofar University, Oman and OIC of Lab of Biochemistry at Department of Biomedical Engineering and Sciences, SMME, NUST, Pakistan. He obtained his B.Pharmacy from the University of Peshawar, Pakistan in 2003. He completed his MS and Ph.D degree from Kyungpook National University, South Korea (2008–2014). He has published over 100 scientific publications and book chapters in refereed journals. Before joining NUST, Dr Adeeb has worked production pharmacist at Glaxo Smith Kline Pvt Ltd, Karachi, Pakistan and Medicraft Pharmaceutical Pvt Ltd, Peshawar, Pakistan from 2003-2007. His research interest is mainly oriented to the screening and development of plant isolated compounds as anticancer agents, as well as investigating the modulation of different signaling pathways in different types of cancers causing drug resistance and poor prognosis. Dr Adeeb is also interesting in development of kits for diagnosis and drug release patches with validation in animal models. Dr Adeeb is working as Editorial board member for several journals and has authored two books with international publishers. He received a number of national and international awards in academics and research.

1. Introduction to cell signaling

Ishtiaq Ali, Muhammad Junaid, Ahmad Tariq, Fazli Wahid, Muhammad Imran Khan

2. Regulation of Cell Signaling Cascades

Habab Ali Ahmad, Muhammad Ibrahim, Fazli Wahid, Muhammad Imran Khan

3. Cellular Receptors and Cell Signaling

Maleeha Azhar, Aroob Hasan Khan, Aroosa Younis Nadeem, Areej Fatima, Adeeb Shehzad

4. Signal Transduction and Integral Membrane Proteins

Zain Saeed, Zohra Jabeen, Sehrish Kakakhel, Saira Justin, Aneela Javed

5. Antigen-Antibody Interaction in cell signaling

Saman Noor, Anam Fatima, Iman Fatima, Gul Naz, Aneela Javed

6. Immunological and Neuron Synapses

Muhammad Salman Khalid, Somia Mazhar, Adeeb Shehzad

7. Rhinoviruses receptors and their interactions

Areej A. Sattar, Ariba Qaiser, Sobia Manzoor

8. Role of ligand and voltage gated ion channels in cell signaling

Maham Maharangaiz, Hira, sadaf Mumtaz, Rumeza hanif, Aneela Javed

9. Hormones and Receptors Interaction in Cell Signaling

Tehmina Bibi, Shahar Bano, Eun Kyoung Seo, Salman Khan

10. Signaling Networks in Development and Differentiation

Aroosa Younis Nadeem, Areej Fatima, Maleeha Azhar, Adeeb Shehzad

11. Cell Signaling and Metabolism

Saadia Zahid*, Sanila Amber, Laila tul Qadar, Akasha Khurshid

12. Inflammatory Signaling and Immune Response

Naseem Zehra, Zia Uddin, Muhammad Imran Amir Zada, Muhammad Ikram

13. Cell Signaling in Cancer

Khoula Sharif Mughal, Nabi Shah, Muhammad Naeem, Muhammad Ikram

14. Cell signaling pathways in endocrine diseases

Gauhar Rehman, Adil Sher

15. Cell Signaling in Neurological Disorders

Muhammad Ibrar Khan, Muhammad Junaid, Salman Khan

16. Cell Signaling and Diagnosis

Areej Fatima, Ammad Jamil, Maleeha Azhar, Aroosa Younis Nadeem, Adeeb Shehzad

17. Signal Transduction and Targeted Therapies

Ayesha Khan, Ayesha Riaz, Asima Saeed, Muhammad Imran Khan

18. Role of cell signaling in drug development

Taimoor Musharaf, Anoosha Ahmed, Muhammad Asim Siddique, Wajahat Sultan Abbasi, Saadia Andleeb

Erscheint lt. Verlag	17.4.2025
Zusatzinfo	17 Tables, black and white; 118 Line drawings, color; 118 Illustrations, color
Verlagsort	London
Sprache	englisch
Maße	178 x 254 mm
Themenwelt	Studium ► Querschnittsbereiche ► Infektiologie / Immunologie
	Naturwissenschaften ► Biologie ► Biochemie
	Naturwissenschaften ► Biologie ► Zellbiologie
ISBN-10	1-032-70744-5 / 1032707445
ISBN-13	978-1-032-70744-0 / 9781032707440
Zustand	Neuware