Surviving Hypoxia

Mechanisms of Control and Adaptation

Peter W. Hochachka, Peter L. Lutz, Thomas J. Sick, Myron Rosenthal (Autoren)

Buch | Hardcover

592 Seiten

1993
Crc Press Inc (Verlag)
978-0-8493-4226-4 (ISBN)

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Surviving Hypoxia: Mechanisms of Control and Adaptation is a synthesis of findings and thoughts concerning hypoxia. The thermodynamics of hypoxia are discussed in detail, including acid-base balance and self-pollution resulting from the accumulation of anaerobic end-products. The book focuses on descriptions and discussions of common facets, contrasting solutions in a variety of physiological hypoxia defense strategies, including those shown by plants, invertebrates, and vertebrates. Special treatment is given to the distinctive problems that hypoxia presents to vulnerable organs such as the kidney, liver, and brain. It also addresses pathological events in addition to protective mechanisms.

Clinical implications of basic research are examined in the book, which provides new insights into underlying pathological processes occuring in hypoxic-induced organ failure and indicates new paths for successful clinical intervention. Surviving Hypoxia: Mechanisms of Control and Adaptation is an excellent reference for all researchers interested in the physiological effects of hypoxia, underlying pathological events, and protective mechanisms.

Hochachka/, Peter W.; Lutz/, Peter L.; Sick/, Thomas J.; Rosenthal/, Myron

Volume Overview: Defense and Adaptational Strategies (P.W. Hochachka, P.L. Lutz, T. Sick, M. Rosenthal, and G. van den Thillart). ADVANTAGEOUS BIOCHEMICAL PATHWAYS. BIOENERGETIC ADVANTAGES. Intracellular Reactions Controlling Environmental Anaerobiosis in the Marine Annelid Arenicola marina, a Fresh Look at Old Pathways (G. Kamp). Aerobic and Anaerobic Energy Metabolism in the Life Cycle of Parasitic Helminths (A.G.M. Tielens and S.G. van den Bergh). Energy Metabolism of Invertebrate Erythrocytes: Anaerobic Metabolism of Blood Clams (A. de Zwaan and P. Cortesi). Rice and Wheat Seedlings as Plant Models of High and Low Tolerance to Anoxia (F. Menegus, L. Cattaruzza, H. Molinari, and E. Ragg). In Vivo Proton NMR of the Brain (W.M.M.J. Bovee, J. van Dijk, H. Slotboom, D. Bosman, and R.A.F.M. Chamuleau). EFFICIENCY ADVANTAGES. Efficiency and Power Strategies Under Hypoxia. Is Low Efficiency at High Glycolitic ATP Production a Paradox? (E. Gnaiger). Effects of Thyroid Hormone on the Energetic Efficiency of Muscle Contraction (C. van Hardeveld and W.S. Simonides). Adaptability of Metabolic Efficiencies Under Chronic Hypoxia in Man (P.W. Hochachka). pH ADVANTAGES. Multicompartmental Analyses of Acid-Base and Metabolic Homeostasis during Anaerobiosis: Invertebrate and Lower Vertebrate Examples (H-O Portner). Ethanol Formation and pH Regulation in Fish (A. van Waarde, G. van den Thillart, and M. Verhagen). pHi and Anabolic Arrest during Anoxia in Artemia franciscana Embryos (S.H. Hand). Interaction between Cytoplasmic Fermentation Reactions and Transport of Protons between Cytoplasm and Vacuoles (J.K.M. Roberts). pH and Metabolic Depression in Mammalian Hibernation. The Example of Brown Adipose Tissue (A. Malan). HYPOXIA DEFENSE AND CONTROL SYSTEMS. Environmental and Exercise Anaerobiosis in Frogs (G. Wegener and U. Krause). The Role of Metabolic Acidosis in the Buffering of ATP by Phosphagen Stores in Fish: An In Vivo NMR Study (G. van den Thillart and A. van Waarde). Molec

Erscheint lt. Verlag	24.3.1993
Zusatzinfo	49 Tables, black and white; 1 Halftones, black and white
Verlagsort	Bosa Roca
Sprache	englisch
Maße	178 x 254 mm
Gewicht	1247 g
Einbandart	gebunden
Themenwelt	Medizinische Fachgebiete ► Innere Medizin ► Kardiologie / Angiologie
Themenwelt	Studium ► 1. Studienabschnitt (Vorklinik) ► Biochemie / Molekularbiologie
ISBN-10	0-8493-4226-0 / 0849342260
ISBN-13	978-0-8493-4226-4 / 9780849342264
Zustand	Neuware