Microglia (eBook)

Physiology, Pathophysiology and Therapeutic Potential

Marie-Ève Tremblay, Alexei Verkhratsky (Herausgeber)

eBook Download: PDF

2024 | 1. Auflage
XIII, 644 Seiten
Springer-Verlag
978-3-031-55529-9 (ISBN)

Infos

The past decade has witnessed a revolution in our understanding of microglia, especially since their roles in the healthy CNS have started to unravel. These cells were shown to actively maintain health, in concert with neurons and other types of CNS cells, providing further insight into their crucial involvement with diseases.  Edited by Drs. Marie-Ève Tremblay and Alexei Verkhratsky, Microglia: Physiology, Pathophysiology and Therapeutic Potential shares with the scientific and medical community the latest discoveries in the microglial research field, with a truly comprehensive collection of  chapters written by the top specialists across five continents. The book begins by explaining briefly what they are, from both historical and evolutionary points of view, and how they can be studied. The first section explains their physiological roles in the maturation, function, and plasticity of the CNS. The second section focuses on their general involvement in neuropathophysiology, and the third section on their critical implication in specific CNS diseases, including neurotrauma, neuropathic pain, ischemia and stroke, infectious diseases, autoimmune diseases, neurodevelopmental and neuropsychiatric disorders, substance use and addiction, sleep disorders, ageing, and neurodegenerative diseases. The fourth section presents their clinical potential as a targeted therapeutic tool for these  CNS diseases.

Produkt-Details

• Erscheint lt. Verlag: 29.8.2024
• Reihe/Serie: Advances in Neurobiology
• Zusatzinfo: XIII, 644 p. 75 illus., 72 illus. in color.
• Sprache: englisch
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Neurologie
• Themenwelt: Studium ► Querschnittsbereiche ► Infektiologie / Immunologie
• Schlagworte: Cell Therapies • Immunometabolism • Metabolites • Microglia • neurodegenerative diseases • Neurodevelopmental Disorders • Neuropathic pain • neurosychiatric disorders • Neurotrauma • Radiotracers • sleep disordres • substance use and addiction
• ISBN-10: 3-031-55529-5 / 3031555295
• ISBN-13: 978-3-031-55529-9 / 9783031555299