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The Role of Brain Dopamine

Buch | Softcover

IX, 55 Seiten

1989 | 1. Softcover reprint of the original 1st ed. 1989
Springer Berlin (Verlag)
978-3-540-50040-7 (ISBN)

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As in other volumes in the series, this newest volume conveys up-to-date knowledge in a clear and straightforward manner. It begins with a survey of the neurobiological functions of the brain, with the emphasis on Parkinson's disease. This is followed by a presentation of the role of dopamine in the regulation of human anterior pituitary function. The final two chapters concentrate on the dopamine receptors: first, the binding sites are characterized and the biochemical and physiological consequences of dopamine-receptor stimulation are discussed and, finally, there is a report on the topology of a dopamine-receptor model that can account comprehensively for agonists and antagonists.

The Role of Dopamine in the Control of Neurobiological Functions.- Parkinson's Disease.- Senile Dementia of the Alzheimer Type.- A DA Hypothesis of Schizophrenia.- DA in Affective Disorders.- References.- Clinical Aspects of Dopamine in the Regulation of Human Anterior Pituitary Function.- Regulation of Prolactin Secretion.- Clinical Features of Hyperprolactinaemia.- Diagnosis of Hyperprolactinaemia.- Natural History of Prolactinomas.- Therapy.- Macroprolactinomas.- Dopamine and LH Secretion.- Dopamine in Growth Hormone Secretion.- Dopamine Agonist Therapy for Acromegaly.- Dopamine and ACTH Secretion.- Conclusions.- References.- Dopamine Receptors in the Central Nervous System.- Receptors and Second Messengers.- Second Messengers and Dopamine Receptors.- Binding Sites for Dopamine Receptor Ligands.- Biochemical and Physiological Manifestations of Dopamine Receptor Stimulation.- Behavioural Manifestations of Dopamine Receptor Stimulation.- Conclusions.- References.- Topology of Dopamine Receptors.- Dopamine Agonists.- Dopamine Antagonists.- Unsolved Problems: D1/D2 Specificity and Partial Agonists.- Conclusion.- References.

Erscheint lt. Verlag	16.10.1989
Reihe/Serie	Basic and Clinical Aspects of Neuroscience
Co-Autor	P. Riederer, E. Sofic, C. Konradi, J. Kornhuber, H. Beckmann, M. Dietl, G. Moll, G. Hebenstreit, M.O. Thorner, M.L. Vance, J.C. Stoof, F.J.H. Tilders, T.J. Petcher
Illustrationen	Jack Haley
Zusatzinfo	IX, 55 p. 30 illus., 29 illus. in color.
Verlagsort	Berlin
Sprache	englisch
Maße	210 x 277 mm
Gewicht	250 g
Themenwelt	Sachbuch/Ratgeber ► Gesundheit / Leben / Psychologie
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Neurologie
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
	Medizin / Pharmazie ► Studium
	Naturwissenschaften ► Biologie ► Humanbiologie
Schlagworte	Alzheimer • biochemistry • Catecholamines • dopamine • nervous system • neurons • Parkinson • Regulation
ISBN-10	3-540-50040-5 / 3540500405
ISBN-13	978-3-540-50040-7 / 9783540500407
Zustand	Neuware