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Rheumatic Diseases -

Rheumatic Diseases

Immunological Mechanisms and Prospects for New Therapies

J. S. H. Gaston (Herausgeber)

Buch | Hardcover
296 Seiten
1999
Cambridge University Press (Verlag)
978-0-521-59327-4 (ISBN)
CHF 186,75 inkl. MwSt
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This authoritative new volume provides a wide-ranging account of the immunological mechanisms that underlie many rheumatic diseases, such as rheumatoid arthritis, ankylosing spondylitis and SLE, and the development of effective and rational new therapies for their treatment.
This authoritative review volume provides a wide-ranging account of the immunological mechanisms that underlie many rheumatic diseases. Advances in our understanding of the immunopathology of diseases such as rheumatoid arthritis, ankylosing spondylitis and SLE, are paving the way for the development of effective and rational new therapies. This exciting prospect is an important stimulus for ground-breaking research into these diseases and the investigation of new therapeutic options. As the first book to focus exclusively on this burgeoning area of clinical research, this is an invaluable and contemporary account for all rheumatologists, clinical immunologists and those seeking to develop effective new therapies to combat rheumatic diseases.

Implications of advances in immunology for understanding the pathogenesis and treatment of rheumatic disease J. S. Hill Gaston; 1. The role of T cells in autoimmune disease R. J. Moots and K. W. Wucherpfennig; 2. The role of MHC antigens in autoimmunity J. H. Buckner and G. T. Nepom; 3. B cells - formation and structure of autoantibodies A. Rahman, F. K. Stevenson and D. A. Isenberg; 4. Role of CD40 in immune responses P. Lane; 5. Manipulation of the T cell immune system via CD28 and CTLA-4 D. M. Samson and L. S. K. Walker; 6. Lymphocyte antigen receptor signal transduction D. R. Alexander; 7. Role of adhesion mechanisms in inflammation C. Pitzalis; 8. Regulation of apoptosis in rheumatic disorders J. McNally, A. K. Vaishnaw and K. B. Elkon; 9. The role of monokines in arthritisW. B. van den Berg and F. J. J. van de Loo; 10. T lymphocyte sub sets in relation to autoimuune disease F. Ramirez, B. Seddon and D. Mason; 11. Complement receptors J. M. Ahearn and A. M. Rosengard; Index.

Erscheint lt. Verlag 28.7.1999
Zusatzinfo 36 Line drawings, unspecified
Verlagsort Cambridge
Sprache englisch
Maße 178 x 255 mm
Gewicht 725 g
Themenwelt Medizinische Fachgebiete Innere Medizin Rheumatologie
ISBN-10 0-521-59327-1 / 0521593271
ISBN-13 978-0-521-59327-4 / 9780521593274
Zustand Neuware
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