Immunology

Clinical Case Studies and Disease Pathophysiology

Warren Strober, Susan R. Gottesman (Autoren)

Buch | Softcover

256 Seiten

2009
Wiley-Blackwell (Verlag)
978-0-471-32659-5 (ISBN)

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Immunology: Clinical Case Studies and Disease Pathophysiology offers a comprehensive, cutting-edge selection of real life immunology case studies for in-depth investigation into the impact of immunology on modern medical diagnosis and treatment.

26 real-life cases illustrate the applications of basic immunology in clinical settings
May be utilized alone or as a companion to Immunology: A Short Course, 7th Edition by Richard Coico and Geofftry Sunshine (ISBN 9781118396919)
Each case study is introduced by clearly written descriptions of the major immunological disorders
Full colour photographs and illustrations complement complete presentation of real data
Includes complete set of problems and discussion questions for each chapter

Warren Strober, M.D., is Section Chief in the Laboratory of Clinical Investigation, Mucosal Immunity Section at the National Institute of Allergy and Infectious Diseases, National Institutes of Health. Susan R.S. Gottesman, M.D., Ph.D., is Associate Professor in the Department of Pathology at SUNY Health Science Center at Brooklyn.

Preface, ix

Contributors, xi

Index of Lessons in Normal Immunity, xiii

INTRODUCTION TO CASE STUDIES: A GUIDE TO USING THIS BOOK, 1

Unit I IMMUNODEFICIENCY DISEASES, 3

INTRODUCTION: ORGANIZATION OF THE IMMUNE SYSTEM AND EVALUATION OF THE IMMUNODEFICIENT PATIENT, 5

1 X-LINKED AGAMMAGLOBULINEMIA (BRUTON’S AGAMMAGLOBULINEMIA), 15

2 SEVERE COMBINED IMMUNODEFICIENCY DISEASE, 27

3 DiGEORGE SYNDROME (CONGENITAL THYMIC APLASIA), 41

4 HYPER-IgM SYNDROME, 53

5 COMMON VARIABLE IMMUNODEFICIENCY DISEASE, 67

6 AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME (ALPS), 81

7 X-LINKED LYMPHOPROLIFERATIVE SYNDROME, 91

8 HEREDITARY ANGIOEDEMA, 101

9 ACQUIRED IMMUNODEFICIENCY SYNDROME, 111

Unit II IMMEDIATE HYPERSENSITIVITY AND MAST CELL DISORDERS, 125

INTRODUCTION: WHEN ANTIGENS BECOME ALLERGENS, 127

10 MASTOCYTOSIS, 129

11 ANAPHYLAXIS, 137

12 ASTHMA, 147

13 THE VASCULITIDES, 161

Unit III AUTOIMMUNE DISORDERS, 173

INTRODUCTION: OVERVIEW OF AUTOIMMUNE DISORDERS AND MECHANISMS OF TOLERANCE, 175

14 MYASTHENIA GRAVIS, 183

15 MULTIPLE SCLEROSIS, 195

16 DIABETES MELLITUS TYPE 1, 207

17 CELIAC DISEASE, 219

18 INFLAMMATORY BOWEL DISEASE, 231

19 PSORIASIS, 245

20 IgA NEPHROPATHY AND KIDNEY TRANSPLANTATION, 255

21 RHEUMATOID ARTHRITIS, 269

22 SYSTEMIC LUPUS ERYTHEMATOSUS, 283

23 SCLERODERMA, 299

Unit IV MALIGNANCIES OF THE LYMPHOID SYSTEM, 309

INTRODUCTION: CLASSIFICATION OF LYMPHOID MALIGNANCIES, 311

24 CHRONIC LYMPHOCYTIC LEUKEMIA/SMALL LYMPHOCYTIC LYMPHOMA, 317

25 FOLLICULAR LYMPHOMA, 327

26 PLASMA CELL NEOPLASMS, 337

Unit V 349

LABORATORY TESTS USED IN THE WORKUP OF PATIENTS WITH IMMUNOLOGIC DISEASES, 351

Index, 369

Erscheint lt. Verlag	21.4.2009
Zusatzinfo	Photos: 0 B&W, 30 Color; Drawings: 0 B&W, 59 Color
Verlagsort	Hoboken
Sprache	englisch
Maße	213 x 277 mm
Gewicht	1157 g
Themenwelt	Studium ► Querschnittsbereiche ► Infektiologie / Immunologie
ISBN-10	0-471-32659-3 / 0471326593
ISBN-13	978-0-471-32659-5 / 9780471326595
Zustand	Neuware