Renal Cell Carcinoma
Seiten
1993
Marcel Dekker Inc (Verlag)
978-0-8247-9033-2 (ISBN)
Marcel Dekker Inc (Verlag)
978-0-8247-9033-2 (ISBN)
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Brings together various aspects of renal cell carcinoma. This book provides a basis for understanding the disease's origin, progression and responses to immunotherapy. Examining the status of cytokine, cell-based and chemotherapeutic methods of treatment, it discusses the clinical presentation of advanced carcinoma and its therapeutic challenges.
This reference brings together all aspects of renal cell carcinoma, and provides a basis for understanding the disease's origin, progression and responses to immunotherapy.;Examining the current status of cytokine, cell-based and chemotherapeutic methods of treatment, this book: discusses the clinical presentation of advanced renal carcinoma and its therapeutic challenges; reviews prognostic factors and the management of renal cell carcinoma occurring with von Hippel-Landau syndrome; summarizes efforts to identify the tumour suppressor gene deleted from chromosome 3 in most renal cell carcinomas; explicates the role of oncogenes in the progression of renal cell cancer and the molecular correlates of responses to interferon-alpha treatment; details the latest laboratory efforts to establish gene therapy for tumour treatment by transfection of cytokine genes in murine model systems; focuses on biologic response modifier therapy in humans, including cell-mediated immune responses and adoptive immunotherapy; presents preclinical and clinical studies of interleukin-2 alone, in combination with othe cytokines, and with chemothrapeutic agents; and addresses studies on the tumour necrosis factor and low- and high-dose interferon-alpha.
This reference brings together all aspects of renal cell carcinoma, and provides a basis for understanding the disease's origin, progression and responses to immunotherapy.;Examining the current status of cytokine, cell-based and chemotherapeutic methods of treatment, this book: discusses the clinical presentation of advanced renal carcinoma and its therapeutic challenges; reviews prognostic factors and the management of renal cell carcinoma occurring with von Hippel-Landau syndrome; summarizes efforts to identify the tumour suppressor gene deleted from chromosome 3 in most renal cell carcinomas; explicates the role of oncogenes in the progression of renal cell cancer and the molecular correlates of responses to interferon-alpha treatment; details the latest laboratory efforts to establish gene therapy for tumour treatment by transfection of cytokine genes in murine model systems; focuses on biologic response modifier therapy in humans, including cell-mediated immune responses and adoptive immunotherapy; presents preclinical and clinical studies of interleukin-2 alone, in combination with othe cytokines, and with chemothrapeutic agents; and addresses studies on the tumour necrosis factor and low- and high-dose interferon-alpha.
The challenge of advanced renal cell carcinoma; clinical features; molecular biology; cell-mediated immune responses and adoptive immunotherapy; interleukin-2 and other cytokines; combination therapy with cytokines; chemotheray and chemoimmunotherapy
| Erscheint lt. Verlag | 23.4.1993 |
|---|---|
| Verlagsort | New York |
| Sprache | englisch |
| Maße | 210 x 280 mm |
| Gewicht | 688 g |
| Themenwelt | Medizinische Fachgebiete ► Innere Medizin ► Nephrologie |
| Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie | |
| Medizin / Pharmazie ► Medizinische Fachgebiete ► Urologie | |
| Studium ► Querschnittsbereiche ► Infektiologie / Immunologie | |
| ISBN-10 | 0-8247-9033-2 / 0824790332 |
| ISBN-13 | 978-0-8247-9033-2 / 9780824790332 |
| Zustand | Neuware |
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