Normal Cytology

An Illustrated, Practical Guide

Madelyn Lew, Judy Pang, Liron Pantanowitz (Herausgeber)

Buch | Softcover

XIII, 174 Seiten

2024 | 1st ed. 2022
Springer International Publishing (Verlag)
978-3-031-20338-1 (ISBN)

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In the practice of cytopathology, cytologists frequently encounter a spectrum of benign, normal cells in samples. In fact, these normal cells frequently comprise the greatest proportion of material present on a cytology slide. This is frequently the case in Pap smears of the uterine cervix , urine samples, and lung samples such as bronchial brushings. Normal cytology can often mimic pathology leading to misdiagnoses, especially in cases with reactive and metaplastic changes. Moreover, cytopathology findings of certain neoplasms can also mimic normal cytology.
Today, cytology laboratories are no longer confined to dealing with just exfoliative specimens and superficial aspirations. With interventional radiology as well as endobronchial and endoscopic ultrasound-guided fine needle aspirations (FNA), we increasingly encounter visceral samples. Hence, cytologists are even likely to encounter normal elements from deep-seated organs. Sometimes, unexpected normalelements may be found within cytology specimens because a FNA procedure has contamination or inadvertently sampled a nearby organ or normal anatomical structure. A typical example is the finding of ganglion cells when a FNA is performed targeting a celiac node for cancer staging (Elgarby EA et al. Frequency and characterization of celiac ganglia diagnosed on fine-needle aspiration. Cytojournal. 2015; 12:4).
Despite the importance of knowing the spectrum of normal cytology, there are limited reference materials available on this topic for cytologists. Most cytopathology texts deal with abnormal cytology. Often, the chapters in these books only devote a few sentences about normal cytology (euplasia). Our proposed book intends to fulfil this need. The book will contain a mixture of text and images (atlas). Important aspects related to cytology practice will be highlighted such as clinical relevance, differential diagnoses, mimics and pitfalls. The images will include a variety of cytology specimen preparations (e.g. direct smears, liquid based samples, touch preparations, cell blocks) and stains (e.g. Diff Quik/MGG, Papanicolaou, H&E). In selected cases, the expected immunoprofile of normal cells will be addressed. Each chapter will also include a modest list of helpful and contemporary references.

Madelyn Lew, MDMichigan Medicine Department of Pathology2800 Plymouth Rd, Bldg 35Ann Arbor, MI 48109Tel: (734)936-6622

Judy C. Pang, MDMichigan Medicine Department of Pathology2800 Plymouth Rd, Bldg 35Ann Arbor, MI 48109Tel: 734-232-0251

Liron Pantanowitz, MD PhD MHAMichigan Medicine Department of Pathology2800 Plymouth Rd, Bldg 35Ann Arbor, MI 48109Tel: 413-237-4397

Introduction.- Respiratory System.- Digestive tract (oral cavity, esophagus, stomach, intestines, and anus).- The Hepatobiliary System.- Exocrine Glands.- The Endocrine Glands.- Lymphoid & hematopoietic systems (nodes, thymus, spleen, bone marrow).- The Urinary Tract.- Female Reproductive System.- Male Reproductive System (prostate, seminal vesicle, and testis).- Breast.- Musculoskeletal System (bone, cartilage, muscle, soft tissue) and Skin.- Body Cavities (mesothelium, synovium).- Central Nervous System, Peripheral Nervous System, and Eye.

Erscheinungsdatum	04.01.2024
Zusatzinfo	XIII, 174 p. 260 illus. in color.
Verlagsort	Cham
Sprache	englisch
Maße	210 x 279 mm
Gewicht	527 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete
Themenwelt	Studium ► 2. Studienabschnitt (Klinik) ► Pathologie
Schlagworte	clinical relevance • liquid based samples • Mesothelium • Parathyroid • touch preparations
ISBN-10	3-031-20338-0 / 3031203380
ISBN-13	978-3-031-20338-1 / 9783031203381
Zustand	Neuware