Pharmacodynamics and Drug Development

Perspectives in Clinical Pharmacology

Neal R. Cutler, John J. Sramek, Prem K. Narang (Herausgeber)

Buch | Hardcover

512 Seiten

1994
John Wiley & Sons Inc (Verlag)
978-0-471-95052-3 (ISBN)

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Spanning many of the major drug classes, this guide explores the key factors of drug development, concentrating on general methodology and regulatory issues. It considers the pharmacology of major receptor types and the pharmacodynamics of a wide range of therapeutic drug classes.

Contains essential facts and concepts spanning many of the important drug classes. Features an authoritative section on general methodology and regulatory issues. The molecular biology and pharmacology of key receptor types are considered along with the detailed pharmacodynamics of a wide range of therapeutic drug groups.

Neal R. Cutler is the editor of Pharmacodynamics and Drug Development: Perspectives in Clinical Pharmacology, published by Wiley. John J. Sramek is the editor of Pharmacodynamics and Drug Development: Perspectives in Clinical Pharmacology, published by Wiley.

Partial table of contents:

OVERVIEW OF PHARMACODYNAMICS.

Basic Pharmacodynamic Concepts and Models (R. Wills).

Factors Influencing Variability in Kinetics and Dynamics (P. Narang& R. Li).

General Perspectives on the Role of Metabolite in Pharmacokineticsand Pharmacodynamics (R. Seifert).

Regulatory Perspective: The Role of Pharmacokinetics andPharmacodynamics (L. Lesko & R. Williams).

APPLICATION OF PHARMACODYNAMICS IN SELECTED THERAPEUTICDOMAINS.

Theoretical Models for Developing Anxiolytics (P. Nickell & T.Uhde).

Pharmacodynamics of Antipsychotic Drugs in Schizophrenia (J. Sramek& G. Simpson).

Antihypertensive Drugs (L. Prisant & A. Carr).

Pharmacodynamics of Antineoplastic Agents (G. Rosner & M.Ratain).

Virology and Antiviral Drug Development (M. Amantea, et al.).

FRONTIERS IN PHARMACODYNAMICS: INSIGHT FROM MOLECULARAPPROACHES.

Muscarinic Receptors: Pharmacological Subtypes, Structure, Functionand Regulation (L. Mei, et al.).

Serotonin Receptor Subtypes (D. Pritchett).

Index.

Erscheint lt. Verlag	13.7.1994
Verlagsort	New York
Sprache	englisch
Maße	160 x 237 mm
Gewicht	907 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
ISBN-10	0-471-95052-1 / 0471950521
ISBN-13	978-0-471-95052-3 / 9780471950523
Zustand	Neuware