A Clinician's Pearls & Myths in Rheumatology

Buch | Hardcover

XXIII, 771 Seiten

2023 | 2nd ed. 2023
Springer International Publishing (Verlag)
978-3-031-23487-3 (ISBN)

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This book builds upon the first edition with new and improved chapters. The book explores the rich assemblage of clinical wisdom from expert rheumatologists from a wide range of specialties including Vasculitis and Sjogren's syndrome. It examines the nuggets or 'pearls' of wisdom gained from collective clinical experience about the diagnosis or treatment of various diseases whilst also aiming to debunk myths that have influenced the practice of rheumatology by many clinicians.

The second edition of A Clinician's Pearls and Myths in Rheumatology is a critical resource for both practitioners and students of rheumatology. This book provides a clear guide for those wishing to take a "deep dive" into the diagnostic and therapeutic elements of rheumatology.

lt;p>John H. Stone MD, MPH. Professor of Medicine, Harvard Medical School. The Edward A. Fox Chair in Medicine, Massachusetts General Hospital, Boston, MA, USA.

He writes: I have had a career-long interest in teaching, research, and clinical care of patients with rheumatic diseases; i.e., inflammatory diseases mediated by patients' overly active immune systems. My work has focused on the systemic vasculitides, particularly ANCA-associated vasculitis and giant cell arteritis; IgG4-related disease (IgG4-RD); and glucocorticoid toxicity. Following medical school at Harvard Medical School, internal medicine training at Johns Hopkins, and a rheumatology fellowship at the University of California-San Francisco, I co-founded and directed the Vasculitis Center at Johns Hopkins University. This Center was the first in the United States to focus on inflammatory diseases of blood vessels such as ANCA-associated vasculitis and giant cell arteritis.

At Johns Hopkins, I directed the first NIH-funded, multi-center clinical trial in granulomatosis with polyangiitis. The results of this trial were published in The New England Journal of Medicine (2005). This trial paved the way for subsequent trials and investigations in vasculitis on an international scale. Work at the Johns Hopkins Vasculitis Center blazed a path for physicians all over the world interested in vasculitis, encouraging them to focus on research in this area. This effort ultimately served as the impetus for dozens of clinical trials in these diseases that have led to substantially better treatments for patients in less than 20 years.

In 2008, I was recruited to become the Director of Clinical Rheumatology at the Massachusetts General Hospital (MGH), where I have continued my interest in vasculitis from the research standpoint and broadened my clinical scope to include the full breadth of rheumatology. I was the Co-Principal Investigator on the Rituximab in ANCA-associated Vasculitis (RAVE) trial, funded by the Immune Tolerance Network at the NIH. This trial led to two New England Journal of Medicine papers and changed the standard of care for remission induction in this disease. RAVE formed the basis of approval of rituximab (Rituxan) by the U.S. Food & Drug Administration (FDA), the European Medicines Agency (EMA) for remission induction in ANCA-associated vasculitis.

Rheumatoid Arthritis.- Rheumatoid Vasculitis.- Adult-Onset Still's Disease.- Juvenile Idiopathic Arthritis.- Monogenic Autoinflammatory Syndromes.- Juvenile Spondyloarthropathy.- Ankylosing Spondylitis.- Psoriatic Arthritis.- Reactive Arthritis.- Systemic Sclerosis (Scleroderma) and Raynaud's Phenomenon.- Nephrogenic Systemic Fibrosis and Other Scleroderma Mimickers.- Sjögren's Syndrome.- Systemic Lupus Erythematosus.- Pediatric Systemic Lupus Erythematosus.- Mixed Connective Tissue Disease.- The Antiphospholipid Syndrome.- Pregnancy in the Rheumatic Diseases.- Inflammatory Myopathies.- Juvenile Dermatomyositis.- Vasculitic Neuropathy.- Pediatric Vasculitis.- Behçet's Syndrome.- The Churg-Strauss Syndrome.- ANCA-Associated Vasculitis.- Cryoglobulinemia.- Polyarteritis Nodosa.- Giant Cell Arteritis and Polymyalgia Rheumatica.- Takayasu's Arteritis.- Primary Angiitis of the Central Nervous System and Reversible Cerebral Vasoconstriction Syndromes.- Thromboangiitis Obliterans (Buerger's Disease).- Less Common Forms of Vasculitis.- Relapsing Polychondritis.- Fibromyalgia.- The Clinical Features of Gout.- Gout Epidemiology.- Gout Treatment.- Calcium Pyrophosphate Dihydrate (CPPD) Crystal Deposition Disease.- Inflammatory Eye Disease.- Immune-Mediated Inner Ear Disease.- Osteoporosis.- Paget's Disease of Bone.- Sarcoidosis.- Osteoarthritis.- Regional Musculoskeletal Complaints.- Low Back and Neck Pain.- Amyloidosis.- The Ehlers-Danlos Syndrome.- Osteonecrosis.

Erscheinungsdatum	01.04.2023
Zusatzinfo	XXIII, 771 p. 426 illus., 320 illus. in color.
Verlagsort	Cham
Sprache	englisch
Maße	210 x 279 mm
Gewicht	2550 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Radiologie / Bildgebende Verfahren
Schlagworte	Arthritis • autoimmune disease • Autoimmune diseases • Bone • Calcium • Diagnosis • epidemiology • Gout • Imaging • necrosis • Osteoarthritis • Osteoporosis • Pain • Rheumatic Diseases • Rheumatoid Arthritis • Sjogren's Syndrome • Sjogren’s Syndrome • Systemic Lupus Erythematosus • therapy • vasculitis
ISBN-10	3-031-23487-1 / 3031234871
ISBN-13	978-3-031-23487-3 / 9783031234873
Zustand	Neuware