Graft vs. Host Disease

James Ferrara, H. Joachim Deeg, Kenneth R. Cooke (Herausgeber)

Buch | Hardcover

668 Seiten

2004 | 3rd edition
Crc Press Inc (Verlag)
978-0-8247-5472-3 (ISBN)

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With detailed contributions from more than 40 leading authorities on the topic, this Third Edition comprehensively explores the immunobiology, pathophysiology, and clinical manifestations of graft-versus-host disease (GvHD)-offering sections revealing the most up-to-date research on immune activation and dysregulation, the pathophysiology of target organ damage, and GvHD prevention and treatment.

James L. Ferrara, Kenneth R. Cooke, H. Joachim Deeg

The Pathophysiology of Graft-vs.-Host Disease. Animal Models of Graft-vs.-Host Disease. Graft-vs.-Host Disease as a Th1-Type Process: Regulation by Th2-Type Cells. Role of T-Cell Costimulation and Regulatory Cells in Allogeneic Hematopoietic Cell Transplantation. Chemokines and Graft-vs.-Host Disease. Graft-vs.-Leukemia Effects. The Immune System in Graft-vs.-Host Disease: Target and Effector Organ. Pathology and Pathogenesis of Cutaneous Graft-vs.-Host Disease. Graft-vs.-Host Disease of the Liver. Intestinal Graft-vs.-Host Disease. The Pathophysiology of Lung Injury After Hematopoietic Stem Cell Transplantation. Clinical Spectrum of Acute Graft-vs.-Host Disease. Role of Minor Histocompatibility Antigens in the Development of Graft-vs.-Host Disease and Graft-vs.-Leukemia Reactivity. Advances in Tissue Typing and Their Potential Impact on GVHD Incidence and Severity. Immunosuppression and Immunophilin Ligands: Cyclosporin, Tacrolimus, and Sirolimus. Prophylaxis and Treatments of Acute Graft-vs.-Host Disease. Graft Manipulation to Prevent Graft-vs.-Host Disease. Graft-vs.-Host Disease in Nonmyeloablative Transplant. Adoptive Immunotherapy in Stem Cell Transplantation. Clinical Spectrum and Therapeutic Approaches to Chronic Graft-vs.-Host Disease. Recent Advances and Future Directions.

Erscheint lt. Verlag	17.12.2004
Zusatzinfo	30 Halftones, black and white
Verlagsort	Bosa Roca
Sprache	englisch
Maße	178 x 254 mm
Gewicht	1292 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Chirurgie
	Studium ► 1. Studienabschnitt (Vorklinik) ► Physiologie
	Studium ► Querschnittsbereiche ► Infektiologie / Immunologie
ISBN-10	0-8247-5472-7 / 0824754727
ISBN-13	978-0-8247-5472-3 / 9780824754723
Zustand	Neuware